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Antioxidant Properties of a Pharmaceutical Substance Hypocard, a Potential Drug for Ischemic Disease
by
Klochkov, S. G.
, Mishchenko, D. V.
, Neganova, M. E.
, Shevtsova, E. F.
, Bogatyrenko, T. N.
in
Animals
/ Antioxidants
/ Antioxidants - metabolism
/ Biomedical and Life Sciences
/ Biomedicine
/ Brain - drug effects
/ Brain - metabolism
/ Cell Biology
/ Internal Medicine
/ Iron
/ Ischemia
/ Laboratory Medicine
/ Lipid Peroxidation - drug effects
/ Male
/ Nicorandil - pharmacology
/ Oxidative Stress - drug effects
/ Oxidative Stress - physiology
/ Pathology
/ Pharmacology and Toxicology
/ Picolines - pharmacology
/ Rats
2018
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Antioxidant Properties of a Pharmaceutical Substance Hypocard, a Potential Drug for Ischemic Disease
by
Klochkov, S. G.
, Mishchenko, D. V.
, Neganova, M. E.
, Shevtsova, E. F.
, Bogatyrenko, T. N.
in
Animals
/ Antioxidants
/ Antioxidants - metabolism
/ Biomedical and Life Sciences
/ Biomedicine
/ Brain - drug effects
/ Brain - metabolism
/ Cell Biology
/ Internal Medicine
/ Iron
/ Ischemia
/ Laboratory Medicine
/ Lipid Peroxidation - drug effects
/ Male
/ Nicorandil - pharmacology
/ Oxidative Stress - drug effects
/ Oxidative Stress - physiology
/ Pathology
/ Pharmacology and Toxicology
/ Picolines - pharmacology
/ Rats
2018
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Antioxidant Properties of a Pharmaceutical Substance Hypocard, a Potential Drug for Ischemic Disease
by
Klochkov, S. G.
, Mishchenko, D. V.
, Neganova, M. E.
, Shevtsova, E. F.
, Bogatyrenko, T. N.
in
Animals
/ Antioxidants
/ Antioxidants - metabolism
/ Biomedical and Life Sciences
/ Biomedicine
/ Brain - drug effects
/ Brain - metabolism
/ Cell Biology
/ Internal Medicine
/ Iron
/ Ischemia
/ Laboratory Medicine
/ Lipid Peroxidation - drug effects
/ Male
/ Nicorandil - pharmacology
/ Oxidative Stress - drug effects
/ Oxidative Stress - physiology
/ Pathology
/ Pharmacology and Toxicology
/ Picolines - pharmacology
/ Rats
2018
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Antioxidant Properties of a Pharmaceutical Substance Hypocard, a Potential Drug for Ischemic Disease
Journal Article
Antioxidant Properties of a Pharmaceutical Substance Hypocard, a Potential Drug for Ischemic Disease
2018
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Overview
Antioxidant activity of a pharmaceutical substance hypocard was compared with activity of nitromalic acid and well-known agents nicorandil and Mexidol. The ability of these substances to inhibit spontaneous and oxidant-induced LPO process in rat brain homogenate was analyzed. The mechanisms of these effects were studied. The antioxidant properties of hypocard manifested in the inhibition of Fe(II)-induced LPO were significantly more pronounced in comparison with Mexidol and nicorandil.
Publisher
Springer US,Springer Nature B.V
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