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The Relationship between Previous Fluoroquinolone Use and Levofloxacin Resistance in Helicobacter pylori Infection

by Bruce, Michael G. , Morris, Julie M. , Reasonover, Alisa L. , Coleman, John M. , McMahon, Brian J. , Carothers, John J. , Hurlburt, Debby A. , Hennessy, Thomas W. , Bensler, Michael , Parkinson, Alan J.

in Adult / Aged / Aged, 80 and over / Anti-Bacterial Agents - pharmacology / Drug Resistance, Multiple, Bacterial / Female / Helicobacter Infections - drug therapy / Helicobacter Infections - microbiology / Helicobacter pylori / Helicobacter pylori - drug effects / Humans / Levofloxacin / Male / Microbial Sensitivity Tests / Middle Aged / Ofloxacin - pharmacology

2007

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The Relationship between Previous Fluoroquinolone Use and Levofloxacin Resistance in Helicobacter pylori Infection

2007

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The Relationship between Previous Fluoroquinolone Use and Levofloxacin Resistance in Helicobacter pylori Infection

2007

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Journal Article

The Relationship between Previous Fluoroquinolone Use and Levofloxacin Resistance in Helicobacter pylori Infection

Bruce, Michael G.,

Morris, Julie M.,

Reasonover, Alisa L.,

Coleman, John M.,

McMahon, Brian J.,

Carothers, John J.,

Hurlburt, Debby A.,

Hennessy, Thomas W.,

Bensler, Michael,

Parkinson, Alan J.

2007

Overview

The relationship between prior fluoroquinolone use and levofloxacin resistance in Helicobacter pylori infection is unknown. Among 125 enrolled patients, 8.8% had H. pylori isolates that were resistant to levofloxacin. Levofloxacin resistance was associated with any prior fluoroquinolone use over the previous 10 years and with the total number of fluoroquinolone courses prescribed (P < .001).

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Publisher

The University of Chicago Press

Subject

Adult

/ Aged

/ Aged, 80 and over

/ Anti-Bacterial Agents - pharmacology

/ Drug Resistance, Multiple, Bacterial

/ Female

/ Helicobacter Infections - drug therapy