Journal Article

Fine-needle cytology in the follow-up of breast carcinoma

Selleri, Carmine, Cascone, Anna Maria, Salzano, Francesco, Siano, Maria, Angrisani, Basilio, Di Crescenzo, Rosa Maria, Vatrella, Alessandro, Zeppa, Pio

2017

Overview

The postoperative follow-up strategies for breast carcinoma (BC) utilize different procedures; the aim of this study was to investigate the role of fine-needle cytology (FNC) in the follow-up of BC patients. Two hundred sixty-six FNC samples from 190 BC patients have been reviewed. The target anatomical sites were 190 breast including 155 ipsilateral and 145 contralateral breast lesions and 76 extra-mammary nodules. Extra-mammary lesions included lymph nodes, thyroidal nodules, soft tissue lesions, (subcutaneous and sub-scars), salivary glands and deep located masses. Diagnostic distribution of the breast lesions was as follows: 51 positive, 15 indeterminate/suspicious, 119 negative and 5 inadequate. Positive cases included 43 ipsilateral and 8 contralateral BC, 9 BC in different quadrants from those of onset of the first BC. Sensitivity, specificity and accuracy have been 90, 91 and 90&, respectively. FNC, in a correct setting, is a reliable and effective method for the follow-up management of BC patients.

• Publisher: Springer International Publishing,Springer Nature B.V
• Subject: Aged / Biopsy, Fine-Needle - methods / Breast cancer / Breast Neoplasms - pathology / Breast Neoplasms - surgery / Cellular biology / Cytodiagnosis - methods / Female / Follow-Up Studies / Geriatrics/Gerontology / Humans / Italy / Male / Mastectomy - adverse effects / Mastectomy - methods / Medicine / Medicine & Public Health / Middle Aged / Neoplasm Metastasis - pathology / Neoplasm Recurrence, Local - pathology / Original Article / Postoperative Period / Reproducibility of Results / Sensitivity and Specificity