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Chemopreventive mechanisms of amentoflavone: recent trends and advancements
by
Sak, Katrin
, Varol, Mehmet
, Ramniwas, Seema
, Rani, Vibha
, Vashishth, Kanupriya
, Tuli, Hardeep Singh
, Joshi, Hemant
, Kumar, Manoj
, Rani, Isha
in
Angiogenesis
/ Antineoplastic Agents - pharmacology
/ Antineoplastic Agents - therapeutic use
/ Antitumor agents
/ Apoptosis
/ Biflavonoids - chemistry
/ Biflavonoids - pharmacology
/ Biflavonoids - therapeutic use
/ Biomedical and Life Sciences
/ Biomedicine
/ Cancer
/ Cell death
/ Chemotherapy
/ Clinical trials
/ Drug development
/ Metastases
/ Neurosciences
/ Pharmacology/Toxicology
/ Review
/ Tumor cells
2023
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Chemopreventive mechanisms of amentoflavone: recent trends and advancements
by
Sak, Katrin
, Varol, Mehmet
, Ramniwas, Seema
, Rani, Vibha
, Vashishth, Kanupriya
, Tuli, Hardeep Singh
, Joshi, Hemant
, Kumar, Manoj
, Rani, Isha
in
Angiogenesis
/ Antineoplastic Agents - pharmacology
/ Antineoplastic Agents - therapeutic use
/ Antitumor agents
/ Apoptosis
/ Biflavonoids - chemistry
/ Biflavonoids - pharmacology
/ Biflavonoids - therapeutic use
/ Biomedical and Life Sciences
/ Biomedicine
/ Cancer
/ Cell death
/ Chemotherapy
/ Clinical trials
/ Drug development
/ Metastases
/ Neurosciences
/ Pharmacology/Toxicology
/ Review
/ Tumor cells
2023
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Chemopreventive mechanisms of amentoflavone: recent trends and advancements
by
Sak, Katrin
, Varol, Mehmet
, Ramniwas, Seema
, Rani, Vibha
, Vashishth, Kanupriya
, Tuli, Hardeep Singh
, Joshi, Hemant
, Kumar, Manoj
, Rani, Isha
in
Angiogenesis
/ Antineoplastic Agents - pharmacology
/ Antineoplastic Agents - therapeutic use
/ Antitumor agents
/ Apoptosis
/ Biflavonoids - chemistry
/ Biflavonoids - pharmacology
/ Biflavonoids - therapeutic use
/ Biomedical and Life Sciences
/ Biomedicine
/ Cancer
/ Cell death
/ Chemotherapy
/ Clinical trials
/ Drug development
/ Metastases
/ Neurosciences
/ Pharmacology/Toxicology
/ Review
/ Tumor cells
2023
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Chemopreventive mechanisms of amentoflavone: recent trends and advancements
Journal Article
Chemopreventive mechanisms of amentoflavone: recent trends and advancements
2023
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Overview
In parallel to the continuous rise of new cancer cases all over the world, the interest of scientific community in natural anticancer agents has steadily been increased. In the past decades, numerous phytochemicals have been shown to possess a strong anticancer potential in preclinical conditions. One of such interesting compounds, derived from different plants such as ginkgo, hinoki, and St. John`s wort, is amentoflavone. In this review article, a wide range of anticancer properties of this natural biflavone are described, revealing its ability to suppress the malignant growth and lead tumor cells to apoptotic death, besides impeding also angiogenic and metastatic processes. Therefore, amentoflavone can be considered a potential lead compound for the development of novel anticancer drug candidates, definitely deserving further in vivo studies and also initiation of clinical trials. It is expected that this plant biflavone might be important, either alone or in combination with the current standard chemotherapeutics, in providing some alleviation for the continuous rise of global cancer burden.
Publisher
Springer Berlin Heidelberg,Springer Nature B.V
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