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Pregnancy and the Autoimmune Patient
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Journal Article
Pregnancy and the Autoimmune Patient
2024
Overview
Purpose of Review
This article will review the current understanding of the immunologic changes that occur during pregnancy. It will discuss the impact of pregnancy on the disease activity of autoimmune or inflammatory rheumatic diseases (AIRD). Lastly, it will highlight the most recent data on pre-conception and pregnancy management practices that can improve pregnancy outcomes in autoimmune patients.
Recent Findings
Pregnancy is an immunologically complex and dynamic state that may affect the activity of AIRDs, with more patients having active disease during pregnancy than previously thought. Uncontrolled inflammatory diseases are associated with poor pregnancy outcomes such as preeclampsia, small for gestational age infants, and prematurity. Pre-conception counseling and early pregnancy planning discussions can help ensure optimal disease control and medication management prior to attempting conception.
Summary
Adequate control of AIRDs on pregnancy-compatible medications during the pre-conception, pregnancy, and postpartum periods is required for optimal pregnancy outcomes.
Publisher
Springer US,Springer Nature B.V
Subject
/ Antigens
/ Asthma
/ Autoimmune Diseases - immunology
/ Autoimmune Diseases - therapy
/ Female
/ Humans
/ Ligands
/ Lupus
/ Medicine
/ Patients
/ Pregnancy Complications - immunology
/ Pregnancy Complications - therapy
/ Review
/ Rheumatic Diseases - drug therapy
/ Rheumatic Diseases - immunology
/ Rheumatic Diseases - therapy
