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ReX: an integrative tool for quantifying and optimizing measurement reliability for the study of individual differences

by Kiar, Gregory , Cho, Jae Wook , Bridgeford, Eric W. , Nikolaidis, Aki , Milham, Michael P. , Xu, Ting , Vogelstein, Joshua T.

in 631/114/794 / 631/378 / Bioinformatics / Biological Microscopy / Biological Techniques / Biomarkers / Biomedical and Life Sciences / Biomedical Engineering/Biotechnology / Brain research / Brief Communication / Design / Gradient flow / Life Sciences / Medical imaging / Nervous system / Neuroimaging / Neurosciences / Optimization / Proteomics / Reliability analysis / Two dimensional flow / Validity

2023

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ReX: an integrative tool for quantifying and optimizing measurement reliability for the study of individual differences

by Kiar, Gregory , Cho, Jae Wook , Bridgeford, Eric W. , Nikolaidis, Aki , Milham, Michael P. , Xu, Ting , Vogelstein, Joshua T.

2023

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ReX: an integrative tool for quantifying and optimizing measurement reliability for the study of individual differences

by Kiar, Gregory , Cho, Jae Wook , Bridgeford, Eric W. , Nikolaidis, Aki , Milham, Michael P. , Xu, Ting , Vogelstein, Joshua T.

2023

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Journal Article

ReX: an integrative tool for quantifying and optimizing measurement reliability for the study of individual differences

Kiar, Gregory,

Cho, Jae Wook,

Bridgeford, Eric W.,

Nikolaidis, Aki,

Milham, Michael P.,

Xu, Ting,

Vogelstein, Joshua T.

2023

Overview

Characterizing multifaceted individual differences in brain function using neuroimaging is central to biomarker discovery in neuroscience. We provide an integrative toolbox, Reliability eXplorer (ReX), to facilitate the examination of individual variation and reliability as well as the effective direction for optimization of measuring individual differences in biomarker discovery. We also illustrate gradient flows, a two-dimensional field map-based approach to identifying and representing the most effective direction for optimization when measuring individual differences, which is implemented in ReX. The Reliability eXplorer is a tool for assessing measurement reliability in neuroimaging studies.

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Publisher

Nature Publishing Group US,Nature Publishing Group

Subject

631/114/794

/ 631/378

/ Bioinformatics

/ Biological Microscopy

/ Biological Techniques

/ Biomarkers

/ Biomedical and Life Sciences