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AI for the prediction of early stages of Alzheimer's disease from neuroimaging biomarkers – A narrative review of a growing field
by
Rudroff, Thorsten
, Klén, Riku
, Rainio, Oona
in
Alzheimer's disease
/ Biomarkers
/ Diagnosis
/ Ethics
/ Longitudinal studies
/ Magnetic resonance imaging
/ Medical imaging
/ Medicine
/ Medicine & Public Health
/ Mild cognitive impairment
/ Neurodegenerative diseases
/ Neuroimaging
/ Neurology
/ Neuroradiology
/ Neurosurgery
/ Positron emission tomography
/ Predictions
/ Prognosis
/ Psychiatry
/ Review Article
/ Standardization
2024
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AI for the prediction of early stages of Alzheimer's disease from neuroimaging biomarkers – A narrative review of a growing field
by
Rudroff, Thorsten
, Klén, Riku
, Rainio, Oona
in
Alzheimer's disease
/ Biomarkers
/ Diagnosis
/ Ethics
/ Longitudinal studies
/ Magnetic resonance imaging
/ Medical imaging
/ Medicine
/ Medicine & Public Health
/ Mild cognitive impairment
/ Neurodegenerative diseases
/ Neuroimaging
/ Neurology
/ Neuroradiology
/ Neurosurgery
/ Positron emission tomography
/ Predictions
/ Prognosis
/ Psychiatry
/ Review Article
/ Standardization
2024
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Do you wish to request the book?
AI for the prediction of early stages of Alzheimer's disease from neuroimaging biomarkers – A narrative review of a growing field
by
Rudroff, Thorsten
, Klén, Riku
, Rainio, Oona
in
Alzheimer's disease
/ Biomarkers
/ Diagnosis
/ Ethics
/ Longitudinal studies
/ Magnetic resonance imaging
/ Medical imaging
/ Medicine
/ Medicine & Public Health
/ Mild cognitive impairment
/ Neurodegenerative diseases
/ Neuroimaging
/ Neurology
/ Neuroradiology
/ Neurosurgery
/ Positron emission tomography
/ Predictions
/ Prognosis
/ Psychiatry
/ Review Article
/ Standardization
2024
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AI for the prediction of early stages of Alzheimer's disease from neuroimaging biomarkers – A narrative review of a growing field
Journal Article
AI for the prediction of early stages of Alzheimer's disease from neuroimaging biomarkers – A narrative review of a growing field
2024
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Overview
Objectives
The objectives of this narrative review are to summarize the current state of AI applications in neuroimaging for early Alzheimer's disease (AD) prediction and to highlight the potential of AI techniques in improving early AD diagnosis, prognosis, and management.
Methods
We conducted a narrative review of studies using AI techniques applied to neuroimaging data for early AD prediction. We examined single-modality studies using structural MRI and PET imaging, as well as multi-modality studies integrating multiple neuroimaging techniques and biomarkers. Furthermore, they reviewed longitudinal studies that model AD progression and identify individuals at risk of rapid decline.
Results
Single-modality studies using structural MRI and PET imaging have demonstrated high accuracy in classifying AD and predicting progression from mild cognitive impairment (MCI) to AD. Multi-modality studies, integrating multiple neuroimaging techniques and biomarkers, have shown improved performance and robustness compared to single-modality approaches. Longitudinal studies have highlighted the value of AI in modeling AD progression and identifying individuals at risk of rapid decline. However, challenges remain in data standardization, model interpretability, generalizability, clinical integration, and ethical considerations.
Conclusion
AI techniques applied to neuroimaging data have the potential to improve early AD diagnosis, prognosis, and management. Addressing challenges related to data standardization, model interpretability, generalizability, clinical integration, and ethical considerations is crucial for realizing the full potential of AI in AD research and clinical practice. Collaborative efforts among researchers, clinicians, and regulatory agencies are needed to develop reliable, robust, and ethical AI tools that can benefit AD patients and society.
Publisher
Springer International Publishing,Springer Nature B.V
Subject
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