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Tibial quantitative ultrasound compared to dual-energy X-ray absorptiometry in preterm infants
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Tibial quantitative ultrasound compared to dual-energy X-ray absorptiometry in preterm infants
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Journal Article
Tibial quantitative ultrasound compared to dual-energy X-ray absorptiometry in preterm infants
2023
Overview
ObjectiveThe gold standard for diagnosing metabolic bone disease in pediatrics is dual-energy x-ray absorptiometry (DXA). Bone quantitative ultrasound (QUS) has increasing applications. This study compared the relationship of DXA to QUS in preterm infants.DesignProspective observational study of preterm infants ≤32 weeks gestation or ≤1800 grams at birth. DXA scans measuring bone mineral content (BMC) and tibial QUS scans measuring bone speed of sound (SOS) were obtained near term gestation.Results41 infants had bone scans at mean corrected gestation 37.7 ± 2.1 weeks. BMC and SOS showed weak inverse correlation (R2 0.163, p < 0.01). BMC and SOS correlated with parameters at corrected gestational age at the time of the bone scans (p < 0.05–0.001). SOS correlated with birth gestational age (p < 0.001), not BMC.ConclusionsA statistically significant weak inverse correlation between DXA and QUS was observed. QUS may have advantages over DXA.
Publisher
Nature Publishing Group
