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Omadacycline for Acute Bacterial Skin and Skin-Structure Infections
by
Das, Anita F
, Loh, Evan
, Gardovskis, J
, O’Riordan, William
, Puljiz, Ivan
, Tzanis, Evan
, Green, Sinikka
, Overcash, J. Scott
, Eckburg, Paul B
, Garrity-Ryan, Lynne
, Villano, Stephen A
, Metallidis, Symeon
, Steenbergen, Judith N
, Manley, Amy
in
Adolescent
/ Adult
/ Aged
/ Aged, 80 and over
/ Anti-Bacterial Agents - adverse effects
/ Anti-Bacterial Agents - therapeutic use
/ Antibiotic resistance
/ Antibiotics
/ Bacteria
/ Clinical trials
/ Double-Blind Method
/ Drug Administration Schedule
/ Drug dosages
/ Drug resistance
/ Drug Resistance, Bacterial
/ Female
/ Gram-positive bacteria
/ Humans
/ Infusions, Intravenous
/ Intention to Treat Analysis
/ Linezolid
/ Linezolid - adverse effects
/ Linezolid - therapeutic use
/ Male
/ Methicillin
/ Methicillin-Resistant Staphylococcus aureus - drug effects
/ Middle Aged
/ Morbidity
/ Patients
/ Pharmaceuticals
/ Skin
/ Skin Diseases, Bacterial - drug therapy
/ Skin Diseases, Bacterial - microbiology
/ Staphylococcus infections
/ Statistical analysis
/ Substance abuse treatment
/ Survival
/ Tetracyclines - adverse effects
/ Tetracyclines - therapeutic use
/ Ulcers
/ Young Adult
2019
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Omadacycline for Acute Bacterial Skin and Skin-Structure Infections
by
Das, Anita F
, Loh, Evan
, Gardovskis, J
, O’Riordan, William
, Puljiz, Ivan
, Tzanis, Evan
, Green, Sinikka
, Overcash, J. Scott
, Eckburg, Paul B
, Garrity-Ryan, Lynne
, Villano, Stephen A
, Metallidis, Symeon
, Steenbergen, Judith N
, Manley, Amy
in
Adolescent
/ Adult
/ Aged
/ Aged, 80 and over
/ Anti-Bacterial Agents - adverse effects
/ Anti-Bacterial Agents - therapeutic use
/ Antibiotic resistance
/ Antibiotics
/ Bacteria
/ Clinical trials
/ Double-Blind Method
/ Drug Administration Schedule
/ Drug dosages
/ Drug resistance
/ Drug Resistance, Bacterial
/ Female
/ Gram-positive bacteria
/ Humans
/ Infusions, Intravenous
/ Intention to Treat Analysis
/ Linezolid
/ Linezolid - adverse effects
/ Linezolid - therapeutic use
/ Male
/ Methicillin
/ Methicillin-Resistant Staphylococcus aureus - drug effects
/ Middle Aged
/ Morbidity
/ Patients
/ Pharmaceuticals
/ Skin
/ Skin Diseases, Bacterial - drug therapy
/ Skin Diseases, Bacterial - microbiology
/ Staphylococcus infections
/ Statistical analysis
/ Substance abuse treatment
/ Survival
/ Tetracyclines - adverse effects
/ Tetracyclines - therapeutic use
/ Ulcers
/ Young Adult
2019
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Omadacycline for Acute Bacterial Skin and Skin-Structure Infections
by
Das, Anita F
, Loh, Evan
, Gardovskis, J
, O’Riordan, William
, Puljiz, Ivan
, Tzanis, Evan
, Green, Sinikka
, Overcash, J. Scott
, Eckburg, Paul B
, Garrity-Ryan, Lynne
, Villano, Stephen A
, Metallidis, Symeon
, Steenbergen, Judith N
, Manley, Amy
in
Adolescent
/ Adult
/ Aged
/ Aged, 80 and over
/ Anti-Bacterial Agents - adverse effects
/ Anti-Bacterial Agents - therapeutic use
/ Antibiotic resistance
/ Antibiotics
/ Bacteria
/ Clinical trials
/ Double-Blind Method
/ Drug Administration Schedule
/ Drug dosages
/ Drug resistance
/ Drug Resistance, Bacterial
/ Female
/ Gram-positive bacteria
/ Humans
/ Infusions, Intravenous
/ Intention to Treat Analysis
/ Linezolid
/ Linezolid - adverse effects
/ Linezolid - therapeutic use
/ Male
/ Methicillin
/ Methicillin-Resistant Staphylococcus aureus - drug effects
/ Middle Aged
/ Morbidity
/ Patients
/ Pharmaceuticals
/ Skin
/ Skin Diseases, Bacterial - drug therapy
/ Skin Diseases, Bacterial - microbiology
/ Staphylococcus infections
/ Statistical analysis
/ Substance abuse treatment
/ Survival
/ Tetracyclines - adverse effects
/ Tetracyclines - therapeutic use
/ Ulcers
/ Young Adult
2019
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Omadacycline for Acute Bacterial Skin and Skin-Structure Infections
Journal Article
Omadacycline for Acute Bacterial Skin and Skin-Structure Infections
2019
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Overview
Treatment for acute bacterial skin and skin-structure infections is becoming more challenging as organisms with antimicrobial resistance become more prevalent. In this randomized trial involving 655 adults with bacterial skin and skin-structure infections, omadacycline was noninferior to linezolid regardless of the causative pathogen, including MRSA.
Publisher
Massachusetts Medical Society
Subject
/ Adult
/ Aged
/ Anti-Bacterial Agents - adverse effects
/ Anti-Bacterial Agents - therapeutic use
/ Bacteria
/ Drug Administration Schedule
/ Female
/ Humans
/ Male
/ Methicillin-Resistant Staphylococcus aureus - drug effects
/ Patients
/ Skin
/ Skin Diseases, Bacterial - drug therapy
/ Skin Diseases, Bacterial - microbiology
/ Survival
/ Tetracyclines - adverse effects
/ Tetracyclines - therapeutic use
/ Ulcers
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