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Tirzepatide as Compared with Semaglutide for the Treatment of Obesity
by
Aronne, Louis J.
, Falcon, Beverly L.
, le Roux, Carel W.
, Das, Sagar
, Senyucel, Cagri
, Horn, Deborah Bade
, Lee, Clare J.
, Gomez Valderas, Elisa
, Dunn, Julia P.
, Ho, Wayne
, Glass, Leonard C.
in
Adipocytes
/ Adult
/ Aged
/ Anti-Obesity Agents - administration & dosage
/ Anti-Obesity Agents - adverse effects
/ Body weight
/ Body Weight - drug effects
/ Clinical Medicine
/ Clinical Medicine General
/ Diabetes mellitus (non-insulin dependent)
/ Diet
/ Drug dosages
/ Endocrinology
/ Female
/ Gastroenterology
/ GLP-1 receptor agonists
/ Glucagon-Like Peptide 1
/ Glucagon-Like Peptide-1 Receptor Agonists - administration & dosage
/ Glucagon-Like Peptide-1 Receptor Agonists - adverse effects
/ Humans
/ Injections, Subcutaneous
/ Male
/ Maximum Tolerated Dose
/ Middle Aged
/ Nutrition
/ Obesity
/ Obesity - diagnosis
/ Obesity - drug therapy
/ Side effects
/ Statistical analysis
/ Tirzepatide - administration & dosage
/ Tirzepatide - adverse effects
/ Treatment Outcome
/ Waist Circumference - drug effects
/ Weight control
/ Weight Loss - drug effects
2025
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Tirzepatide as Compared with Semaglutide for the Treatment of Obesity
by
Aronne, Louis J.
, Falcon, Beverly L.
, le Roux, Carel W.
, Das, Sagar
, Senyucel, Cagri
, Horn, Deborah Bade
, Lee, Clare J.
, Gomez Valderas, Elisa
, Dunn, Julia P.
, Ho, Wayne
, Glass, Leonard C.
in
Adipocytes
/ Adult
/ Aged
/ Anti-Obesity Agents - administration & dosage
/ Anti-Obesity Agents - adverse effects
/ Body weight
/ Body Weight - drug effects
/ Clinical Medicine
/ Clinical Medicine General
/ Diabetes mellitus (non-insulin dependent)
/ Diet
/ Drug dosages
/ Endocrinology
/ Female
/ Gastroenterology
/ GLP-1 receptor agonists
/ Glucagon-Like Peptide 1
/ Glucagon-Like Peptide-1 Receptor Agonists - administration & dosage
/ Glucagon-Like Peptide-1 Receptor Agonists - adverse effects
/ Humans
/ Injections, Subcutaneous
/ Male
/ Maximum Tolerated Dose
/ Middle Aged
/ Nutrition
/ Obesity
/ Obesity - diagnosis
/ Obesity - drug therapy
/ Side effects
/ Statistical analysis
/ Tirzepatide - administration & dosage
/ Tirzepatide - adverse effects
/ Treatment Outcome
/ Waist Circumference - drug effects
/ Weight control
/ Weight Loss - drug effects
2025
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Tirzepatide as Compared with Semaglutide for the Treatment of Obesity
by
Aronne, Louis J.
, Falcon, Beverly L.
, le Roux, Carel W.
, Das, Sagar
, Senyucel, Cagri
, Horn, Deborah Bade
, Lee, Clare J.
, Gomez Valderas, Elisa
, Dunn, Julia P.
, Ho, Wayne
, Glass, Leonard C.
in
Adipocytes
/ Adult
/ Aged
/ Anti-Obesity Agents - administration & dosage
/ Anti-Obesity Agents - adverse effects
/ Body weight
/ Body Weight - drug effects
/ Clinical Medicine
/ Clinical Medicine General
/ Diabetes mellitus (non-insulin dependent)
/ Diet
/ Drug dosages
/ Endocrinology
/ Female
/ Gastroenterology
/ GLP-1 receptor agonists
/ Glucagon-Like Peptide 1
/ Glucagon-Like Peptide-1 Receptor Agonists - administration & dosage
/ Glucagon-Like Peptide-1 Receptor Agonists - adverse effects
/ Humans
/ Injections, Subcutaneous
/ Male
/ Maximum Tolerated Dose
/ Middle Aged
/ Nutrition
/ Obesity
/ Obesity - diagnosis
/ Obesity - drug therapy
/ Side effects
/ Statistical analysis
/ Tirzepatide - administration & dosage
/ Tirzepatide - adverse effects
/ Treatment Outcome
/ Waist Circumference - drug effects
/ Weight control
/ Weight Loss - drug effects
2025
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Tirzepatide as Compared with Semaglutide for the Treatment of Obesity
Journal Article
Tirzepatide as Compared with Semaglutide for the Treatment of Obesity
2025
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Overview
In this phase 3b, open-label, randomized, controlled trial involving adults with obesity without type 2 diabetes, tirzepatide was superior to semaglutide in reducing body weight and waist circumference.
Publisher
Massachusetts Medical Society
Subject
/ Adult
/ Aged
/ Anti-Obesity Agents - administration & dosage
/ Anti-Obesity Agents - adverse effects
/ Diabetes mellitus (non-insulin dependent)
/ Diet
/ Female
/ Glucagon-Like Peptide-1 Receptor Agonists - administration & dosage
/ Glucagon-Like Peptide-1 Receptor Agonists - adverse effects
/ Humans
/ Male
/ Obesity
/ Tirzepatide - administration & dosage
/ Tirzepatide - adverse effects
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