Asset Details

MbrlCatalogueTitleDetail

Do you wish to reserve the book?

Spironolactone for Heart Failure with Preserved Ejection Fraction

by Heitner, John F , Desai, Akshay S , Assmann, Susan F , O'Meara, Eileen , Claggett, Brian , McKinlay, Sonja M , Probstfield, Jeffrey L , Fleg, Jerome L , Pfeffer, Marc A , Shaburishvili, Tamaz , Harty, Brian , Kenwood, Christopher T , Shah, Sanjiv J , Yang, Song , Clausell, Nadine , Anand, Inder S , Solomon, Scott D , Boineau, Robin , Gordeev, Ivan , Pitt, Bertram , Lewis, Eldrin F , Diaz, Rafael , Sweitzer, Nancy K

in Aged / Aged, 80 and over / Cardiovascular Diseases - mortality / Clinical outcomes / Creatinine / Dialysis / Double-Blind Method / Drug therapy / Ejection fraction / Female / Follow-Up Studies / Heart attacks / Heart diseases / Heart failure / Heart Failure - drug therapy / Heart Failure - mortality / Heart Failure - physiopathology / Hospitalization - statistics & numerical data / Humans / Hyperkalemia / Hypokalemia / Incidence / Kaplan-Meier Estimate / Male / Middle Aged / Mineralocorticoid Receptor Antagonists - adverse effects / Mineralocorticoid Receptor Antagonists - therapeutic use / Mortality / Patients / Spironolactone - adverse effects / Spironolactone - therapeutic use / Stroke Volume / Treatment Failure / Ventricle

2014

Yes Please

Hey, we have placed the reservation for you!

By the way, why not check out events that you can attend while you pick your title.

Oops! Something went wrong.

Looks like we were not able to place the reservation. Kindly try again later.

Are you sure you want to remove the book from the shelf?

Spironolactone for Heart Failure with Preserved Ejection Fraction

2014

Confirm

Do you wish to request the book?

Spironolactone for Heart Failure with Preserved Ejection Fraction

2014

Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy

How would you like to get it?

Submit

We have requested the book for you!

Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.

Oops! Something went wrong.

Looks like we were not able to place your request. Kindly try again later.

Journal Article

Spironolactone for Heart Failure with Preserved Ejection Fraction

Heitner, John F,

Desai, Akshay S,

Assmann, Susan F,

O'Meara, Eileen,

Claggett, Brian,

McKinlay, Sonja M,

Probstfield, Jeffrey L,

Fleg, Jerome L,

Pfeffer, Marc A,

Shaburishvili, Tamaz,

Harty, Brian,

Kenwood, Christopher T,

Shah, Sanjiv J,

Yang, Song,

Clausell, Nadine,

Anand, Inder S,

Solomon, Scott D,

Boineau, Robin,

Gordeev, Ivan,

Pitt, Bertram,

Lewis, Eldrin F,

Diaz, Rafael,

Sweitzer, Nancy K

2014

Overview

In this trial, 3445 patients with heart failure and a preserved ejection fraction were assigned to spironolactone or placebo. At a mean of 3.3 years, there was no significant difference in death from cardiovascular causes, aborted cardiac arrest, or hospitalization for heart failure. Many patients with heart failure have a normal or near-normal left ventricular ejection fraction. 1 – 4 Such patients share common signs and symptoms, as well as an impaired quality of life and a poor prognosis, with patients who have heart failure and a reduced ejection fraction. 5 – 8 However, the benefit of most medical therapies for heart failure is limited to those with a reduced ejection fraction, generally 40% or less. 1 , 2 , 9 The lack of favorable evidence from clinical-outcome trials involving patients with heart failure and a preserved left ventricular ejection fraction is reflected in current guidelines, which offer no specific . . .

Share this book

Add to My Shelf

Publisher

Massachusetts Medical Society

Subject

Aged

/ Aged, 80 and over

/ Cardiovascular Diseases - mortality

/ Clinical outcomes

/ Creatinine

/ Dialysis

/ Double-Blind Method