Journal Article

Injectable hydrogels for anti-tumour treatment: a review

Xie, Chaoming, Lu, Xiong, He, Huan

2020

Overview

Injectable hydrogels have become the material of choice for the treatment of solid tumours based on their advantages in loading anti-tumour materials. This study reviews the main scientific research achievements on anti-tumour injectable hydrogels in recent years. The gel-forming mechanism of anti-tumour injectable hydrogels was listed, and the advantages and difficulties of each gel-forming mechanism were summarised. In addition, several current anti-tumour methods based on injectable hydrogels were discussed, including chemotherapy, hyperthermia-based therapy, catalytic therapy and immune therapy, as well as the integration of diagnosis and treatment to monitor the progress of cancer treatment. The anti-tumour mechanism and the advantages and disadvantages of various tumour treatments were analysed. Finally, the future development trend of injectable hydrogels for anti-tumour therapy was discussed.

• Publisher: The Institution of Engineering and Technology,John Wiley & Sons, Inc,Wiley
• Subject: anti-tumour injectable hydrogels / anti-tumour mechanism / anti-tumour therapy / anti-tumour treatment / Biocompatibility / Body fluids / Body temperature / cancer / Cancer therapies / cellular biophysics / Chemotherapy / current anti-tumour methods / Drugs / Enzymes / gel-forming mechanism / Heat / Hydrogels / hyperthermia / loading anti-tumour materials / Nanoparticles / patient treatment / Polyethylene glycol / Polymers / radiation therapy / Review Article / solid tumours / Thermotherapy / Toxicity / Tumors / tumour treatments / tumours