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Malignant endocrine tumor of the pancreas associated with von Recklinghausen's disease
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Malignant endocrine tumor of the pancreas associated with von Recklinghausen's disease
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Journal Article
Malignant endocrine tumor of the pancreas associated with von Recklinghausen's disease
2002
Overview
We describe a case of malignant endocrine tumor of the pancreas associated with von Recklinghausen's disease. A 66-year-old woman with familial von Recklinghausen's disease was admitted to our hospital with weight loss and lower abdominal pain. Endoscopy revealed a submucosal tumor in the second part of the duodenum. Contrast-enhanced computed tomography showed a heterogeneous low-density tumor, measuring 20 x 15 mm, in the head of the pancreas, and metastatic lymphadenopathy. Angiography showed faint tumor staining without encasement or apparent increase in vascularity. Pancreatoduodenectomy was performed. Macroscopically, there was a solid tumor, measuring 20 x 18 mm, in the head of the pancreas. Histologically, a malignant endocrine tumor was shown, with direct invasion to the duodenum, and lymph node metastases. This is the thirteenth case of pancreatic malignant tumor and the fourth case of pancreatic endocrine tumor associated with von Recklinghausen's disease reported in the world literature.
Publisher
Springer Nature B.V
Subject
/ Antineoplastic Combined Chemotherapy Protocols - therapeutic use
/ Duodenal Neoplasms - diagnosis
/ Duodenal Neoplasms - therapy
/ Endocrine Gland Neoplasms - complications
/ Endocrine Gland Neoplasms - diagnosis
/ Endocrine Gland Neoplasms - pathology
/ Endocrine Gland Neoplasms - therapy
/ Female
/ Humans
/ malignant endocrine tumor of the pancreas
/ Neurofibromatosis 1 - complications
/ Pancreatic Neoplasms - complications
/ Pancreatic Neoplasms - diagnosis
/ Pancreatic Neoplasms - pathology
