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Infection Rate and Outcomes of Watchman Devices: Results from a Single-Center 14-Year Experience
by
DeSimone, Daniel C.
, Ward, Robert C.
, Baddour, Larry M.
, Holmes Jr, David R.
, Ponamgi, Shiva
, McGill, Trevon
, Adel, Fadi
, DeSimone, Christopher V.
, Asirvatham, Samuel J.
in
Antibiotics
/ Bacteremia
/ Bleeding
/ Brief Report
/ Cardiac arrhythmia
/ Case reports
/ College professors
/ Endocarditis
/ Fibrillation
/ Hemorrhage
/ Infections
/ Medicine
/ Patients
/ Risk factors
/ Royalties
/ Sepsis
/ Surveillance
/ watchman device
2021
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Infection Rate and Outcomes of Watchman Devices: Results from a Single-Center 14-Year Experience
by
DeSimone, Daniel C.
, Ward, Robert C.
, Baddour, Larry M.
, Holmes Jr, David R.
, Ponamgi, Shiva
, McGill, Trevon
, Adel, Fadi
, DeSimone, Christopher V.
, Asirvatham, Samuel J.
in
Antibiotics
/ Bacteremia
/ Bleeding
/ Brief Report
/ Cardiac arrhythmia
/ Case reports
/ College professors
/ Endocarditis
/ Fibrillation
/ Hemorrhage
/ Infections
/ Medicine
/ Patients
/ Risk factors
/ Royalties
/ Sepsis
/ Surveillance
/ watchman device
2021
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Infection Rate and Outcomes of Watchman Devices: Results from a Single-Center 14-Year Experience
by
DeSimone, Daniel C.
, Ward, Robert C.
, Baddour, Larry M.
, Holmes Jr, David R.
, Ponamgi, Shiva
, McGill, Trevon
, Adel, Fadi
, DeSimone, Christopher V.
, Asirvatham, Samuel J.
in
Antibiotics
/ Bacteremia
/ Bleeding
/ Brief Report
/ Cardiac arrhythmia
/ Case reports
/ College professors
/ Endocarditis
/ Fibrillation
/ Hemorrhage
/ Infections
/ Medicine
/ Patients
/ Risk factors
/ Royalties
/ Sepsis
/ Surveillance
/ watchman device
2021
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Infection Rate and Outcomes of Watchman Devices: Results from a Single-Center 14-Year Experience
Journal Article
Infection Rate and Outcomes of Watchman Devices: Results from a Single-Center 14-Year Experience
2021
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Overview
The Watchman device (WD) is a commonly used alternative strategy to oral anticoagulation for stroke risk reduction in patients with atrial fibrillation who have an increased bleeding risk. There are rare case reports of WD-related infection. Currently, there is no formal study that has systematically evaluated the incidence and outcomes WD-related infections. The objective of this study was to evaluate the incidence, risk factors, and outcomes for WD-associated infections in a single-center cohort over a 14-year period. All patients who underwent WD implantation over a 14-year study period (July 2004 through December 2018) comprised our cohort. Baseline characteristics, procedural data, and postimplantation events were identified through a retrospective chart review. Primary study outcomes included WD-related infection, other cardiovascular device-related infection, bacteremia, and mortality. A total of 181 patients (119 males; 65.7%) with a mean age of 75 years at implantation were included in the analysis. A total of 534.7 patient years of follow-up was accrued, with an average of 2.9 years per patient. The most common indications for implantation included gastrointestinal bleeding (56 patients; 30.9%) and intracerebral bleeding (51 patients; 28.2%). During the follow-up period, 37 (20.4%) patients died. Six developed evidence of bacteremia. Only 1 developed an implantable cardioverter defibrillator infection that required a complete system extraction. None of the cohort developed a WD-related device infection during the study period. We concluded that there is a low risk of WD-related infection even in the setting of a blood stream infection.
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