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Additional Follow-up from the ABCD Trial in Patients with Type 2 Diabetes and Hypertension
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Additional Follow-up from the ABCD Trial in Patients with Type 2 Diabetes and Hypertension
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Journal Article
Additional Follow-up from the ABCD Trial in Patients with Type 2 Diabetes and Hypertension
2000
Overview
To the Editor:
In 1998 we presented data from the Appropriate Blood Pressure Control in Diabetes (ABCD) trial on the effect of nisoldipine as compared with enalapril on cardiovascular outcomes after five years of follow-up in 470 patients with hypertension and type 2 diabetes.
1
The nisoldipine therapy was terminated in the cohort with hypertension on July 14, 1997, as recommended by the study's data and safety monitoring committee. At that time, there had been 25 myocardial infarctions in the nisoldipine group, as compared with 5 myocardial infarctions in the enalapril group, resulting in an unadjusted risk ratio of 5.5 (95 . . .
Publisher
Massachusetts Medical Society
Subject
Angiotensin-Converting Enzyme Inhibitors - therapeutic use
/ Calcium Channel Blockers - therapeutic use
/ Cardiovascular Diseases - mortality
/ Diabetes Mellitus, Type 2 - complications
/ Heart Failure - epidemiology
/ Humans
/ Hypertension - complications
/ Myocardial Infarction - epidemiology
