Asset Details
Do you wish to reserve the book?
Microwave-synthesized NiZrO3@GNP and NiZrO3@MWCNT nanocomposites: enhanced antimicrobial efficacy against biofilms and Mycobacterium smegmatis
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Microwave-synthesized NiZrO3@GNP and NiZrO3@MWCNT nanocomposites: enhanced antimicrobial efficacy against biofilms and Mycobacterium smegmatis
Do you wish to request the book?
Microwave-synthesized NiZrO3@GNP and NiZrO3@MWCNT nanocomposites: enhanced antimicrobial efficacy against biofilms and Mycobacterium smegmatis
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Microwave-synthesized NiZrO3@GNP and NiZrO3@MWCNT nanocomposites: enhanced antimicrobial efficacy against biofilms and Mycobacterium smegmatis
2025
Overview
The persistent challenge posed by antibiotic-resistant bacteria and tuberculosis necessitates innovative approaches to antimicrobial treatment. This study explores the synthesis and characterization of NiZrO₃ nanoparticles integrated with graphene nanoplatelets (GNP) and multi-walled carbon nanotubes (MWCNT), using a microwave-assisted green synthesis route, employing fenugreek (
Trigonella foenum-graecum
) seed extract as a gelling agent. The synthesised nanocomposites were systematically analyzed using XRD, FT-IR, Raman spectroscopy, HR-SEM and HR TEM analysis to assess structural, optical, and morphological properties. The antimicrobial and antibiofilm efficacy was evaluated against drug-resistant strains, including
Escherichia coli
and
Klebsiella pneumoniae
, by well diffusion method and crystal violet—Microtitre plate (CV-MtP) method. Notably, the NiZrO₃@MWCNT composite exhibited a maximum antibacterial inhibition zone of 13 mm and showed superior biofilm inhibition of 92.8% against K. pneumoniae at 500 ppm. In contrast, NiZrO₃@GNP demonstrated a biofilm inhibition of 97% at 500 ppm. Furthermore, the microplate Alamar Blue assay (MABA) was employed to determine the minimum inhibitory concentration (MIC) against
Mycobacterium smegmatis
(MTS) with NiZrO₃@MWCNT achieving 96% inhibition and at 500 ppm. These results confirm the enhanced antimicrobial efficacy of the carbon-integrated nanocomposites over pure NiZrO₃, which showed limited activity. This research underscores the promise of NiZrO₃-based nanocomposites as advanced antimicrobial agents, offering a novel strategy to combat the global health threat of antibiotic resistance.
Publisher
Springer International Publishing,Springer
