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Individual sensitivity of cold pressor, environmental meteorological factors associated with blood pressure and its fluctuation
Individual sensitivity of cold pressor, environmental meteorological factors associated with blood pressure and its fluctuation
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Individual sensitivity of cold pressor, environmental meteorological factors associated with blood pressure and its fluctuation
Individual sensitivity of cold pressor, environmental meteorological factors associated with blood pressure and its fluctuation

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Individual sensitivity of cold pressor, environmental meteorological factors associated with blood pressure and its fluctuation
Individual sensitivity of cold pressor, environmental meteorological factors associated with blood pressure and its fluctuation
Journal Article

Individual sensitivity of cold pressor, environmental meteorological factors associated with blood pressure and its fluctuation

2020
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Overview
Previous studies have examined the associations of meteorological factors with blood pressure; however, these associations have not fully elucidated, especially lacking of evidence from cohort study, little information about the associations of cold pressor sensitivity with blood pressure and its fluctuation. The objective of this study was to investigate the outdoor and indoor temperature, barometric pressure, humidity, and cold pressor sensitivity with blood pressure and its fluctuation. Forty-eight healthy subjects were recruited, and response of blood pressure to cold exposure was measured with cold pressor test (CPT). Then, all the subjects were followed up, and blood pressure was measured every half a month in a period of consecutive 12 months. Multiple panel analysis with random-effects generalized least squares (GLS) regression was used to analyze the effect of the outdoor and indoor temperature, barometric pressure, humidity, and response to cold pressor exposure on blood pressure. Outdoor and indoor temperature and humidity were found to be independently associated with blood pressure (all the P values < 0.05). The response to cold exposure positively associated with blood pressure and its fluctuation (P < 0.05). The subjects with higher cold pressor sensitivity had about 4.7 mmHg higher maximum difference of SBP in 1 year than the subjects with lower sensitivity. Outdoor and indoor temperature, humidity, and response to cold exposure are associated with blood pressure and its fluctuation. These findings provided extending evidence on blood pressure management in clinic and preventive practice.