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Image quality of lung perfusion with photon-counting-detector CT: comparison with dual-source, dual-energy CT
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Image quality of lung perfusion with photon-counting-detector CT: comparison with dual-source, dual-energy CT
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Journal Article
Image quality of lung perfusion with photon-counting-detector CT: comparison with dual-source, dual-energy CT
2024
Overview
Purpose
To evaluate the quality of lung perfusion imaging obtained with photon-counting-detector CT (PCD-CT) in comparison with dual-source, dual-energy CT (DECT).
Methods
Seventy-one consecutive patients scanned with PCD-CT were compared to a paired population scanned with dual-energy on a 3rd-generation DS-CT scanner using (a) for DS-CT (Group 1): collimation: 64 × 0.6 × 2 mm; pitch: 0.55; (b) for PCD-CT (Group 2): collimation: 144 × 0.4 mm; pitch: 1.5; single-source acquisition. The injection protocol was similar in both groups with the reconstruction of perfusion images by subtraction of high- and low-energy virtual monoenergetic images.
Results
Compared to Group 1, Group 2 examinations showed: (a) a shorter duration of data acquisition (0.93 ± 0.1 s vs 3.98 ± 0.35 s;
p
< 0.0001); (b) a significantly lower dose-length-product (172.6 ± 55.14 vs 339.4 ± 75.64 mGy·cm;
p
< 0.0001); and (c) a higher level of objective noise (
p
< 0.0001) on mediastinal images.
On perfusion images: (a) the mean level of attenuation did not differ (
p
= 0.05) with less subjective image noise in Group 2 (
p
= 0.049); (b) the distribution of scores of fissure visualization differed between the 2 groups (
p
< 0.0001) with a higher proportion of fissures sharply delineated in Group 2 (
n
= 60; 84.5% vs
n
= 26; 26.6%); (c) the rating of cardiac motion artifacts differed between the 2 groups (
p
< 0.0001) with a predominance of examinations rated with mild artifacts in Group 2 (
n
= 69; 97.2%) while the most Group 1 examinations showed moderate artifacts (
n
= 52; 73.2%).
Conclusion
PCD-CT acquisitions provided similar morphologic image quality and superior perfusion imaging at lower radiation doses.
Clinical relevance statement
The improvement in the overall quality of perfusion images at lower radiation doses opens the door for wider applications of lung perfusion imaging in clinical practice.
Key Points
The speed of data acquisition with PCD-CT accounts for mild motion artifacts
.
Sharply delineated fissures are depicted on PCD-CT perfusion images
.
High-quality perfusion imaging was obtained with a 52% dose reduction
.
Publisher
Springer Berlin Heidelberg,Springer Nature B.V,Springer Verlag
