Journal Article

Descriptive epidemiology of 399 histologically confirmed newly diagnosed meningeal solitary fibrous tumours and haemangiopericytomas in France: 2006–2015

Lottin, Marine, Bauchet, Luc, Figarella-Branger, Dominique, Khettab, Mohamed, Mathieu-Daudé, Hélène, Peyre, Mathieu, Darlix, Amélie, Rigau, Valérie, Boetto, Julien, Pallud, Johan, Zouaoui, Sonia, Champeaux Depond, Charles, Bauchet, Fabienne, Taillandier, Luc, Trétarre, Brigitte

2024

Overview

Purpose Meningeal solitary fibrous tumour (SFT) and haemangiopericytoma (HPC) are uncommon tumours that have been merged into a single entity in the last 2021 WHO Classification of Tumors of the Central Nervous System. To describe the epidemiology of SFT/HPC operated in France and, to assess their incidence. Methods We processed the French Brain Tumour Database (FBTDB) to conduct a nationwide population-based study of all histopathologically confirmed SFT/HPC between 2006 and 2015. Results Our study included 399 SFT/HPC patients, operated in France between 2006 and 2015, in one of the 46 participating neurosurgical centres. The incidence reached 0.062, 95% CI[0.056–0.068] for 100,000 person-years. SFT accounted for 35.8% and, HPC for 64.2%. The ratio of SFT/HPC over meningioma operated during the same period was 0.013. SFT/HPC are about equally distributed in women and men (55.9% vs. 44.1%). For the whole population, mean age at surgery was 53.9 (SD ± 15.8) years. The incidence of SFT/HPC surgery increases with the age and, is maximal for the 50–55 years category. Benign SFT/HPC accounted for 65.16%, SFT/HPC of uncertain behaviour for 11.53% and malignant ones for 23.31%. The number of resection progresses as the histopathological behaviour became more aggressive. 6.7% of the patients with a benign SFT/HPC had a second surgery vs. 16.6% in case of uncertain behaviour and, 28.4% for malignant SFT/HPC patients. Conclusion Meningeal SFT and HPC are rare CNS mesenchymal tumours which both share common epidemiological characteristics, asserting their merging under a common entity. SFT/HPC incidence is less that one case for 1 billion per year and, for around 100 meningiomas-like tumours removed, one SFT/HPC may be diagnosed. SFT/HPC are equally distributed in women and men and, are mainly diagnosed around 50–55 years. The more aggressive the tumour, the higher the probability of recurrence.

• Publisher: Springer Vienna,Springer Nature B.V,Springer Verlag
• Subject: Adolescent / Adult / Aged / Aged, 80 and over / Aggressive behavior / Brain cancer / Brain tumors / Cancer / Central nervous system / Child / Cognitive science / Epidemiology / Female / France - epidemiology / Hemangiopericytoma - diagnosis / Hemangiopericytoma - epidemiology / Hemangiopericytoma - pathology / Hemangiopericytoma - surgery / Human health and pathology / Humans / Incidence / Interventional Radiology / Life Sciences / Male / Medicine / Medicine & Public Health / Meningeal Neoplasms - diagnosis / Meningeal Neoplasms - epidemiology / Meningeal Neoplasms - pathology / Meningeal Neoplasms - surgery / Meningioma / Meningioma - diagnosis / Meningioma - epidemiology / Meningioma - pathology / Meningioma - surgery / Middle Aged / Minimally Invasive Surgery / Neurology / Neuroradiology / Neuroscience / Neurosurgery / Population studies / Santé publique et épidémiologie / Solitary Fibrous Tumors - diagnosis / Solitary Fibrous Tumors - epidemiology / Solitary Fibrous Tumors - pathology / Solitary Fibrous Tumors - surgery / Surgery / Surgical Orthopedics / Tumors / Young Adult