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Bedaquiline and Repurposed Drugs for Fluoroquinolone-Resistant Multidrug-Resistant Tuberculosis: How Much Better Are They?
Bedaquiline and Repurposed Drugs for Fluoroquinolone-Resistant Multidrug-Resistant Tuberculosis: How Much Better Are They?
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Bedaquiline and Repurposed Drugs for Fluoroquinolone-Resistant Multidrug-Resistant Tuberculosis: How Much Better Are They?
Bedaquiline and Repurposed Drugs for Fluoroquinolone-Resistant Multidrug-Resistant Tuberculosis: How Much Better Are They?

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Bedaquiline and Repurposed Drugs for Fluoroquinolone-Resistant Multidrug-Resistant Tuberculosis: How Much Better Are They?
Bedaquiline and Repurposed Drugs for Fluoroquinolone-Resistant Multidrug-Resistant Tuberculosis: How Much Better Are They?
Journal Article

Bedaquiline and Repurposed Drugs for Fluoroquinolone-Resistant Multidrug-Resistant Tuberculosis: How Much Better Are They?

2018
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Overview
[...]long-term follow-up studies have shown that patients who have experienced previous treatment failure contribute importantly to ongoing transmission in the community (2). The study was approved by the relevant health authorities in Armenia and met the exemption criteria set by the MSF ethics review board for a posteriori analyses of routinely collected clinical data. The inverseprobability-weighted regression adjustment analysis showed that patients in the CU cohort had an estimated statistically significant increase in treatment success of 30.2% (95% confidence interval, 15.8-44.5%). [...]new and repurposed drugs can make fluoroquinoloneresistant MDR-TB, and potentially XDR-TB, a disease that is curable in the majority of cases.