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Deep-Brain Stimulation — Entering the Era of Human Neural-Network Modulation
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Deep-Brain Stimulation — Entering the Era of Human Neural-Network Modulation
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Deep-Brain Stimulation — Entering the Era of Human Neural-Network Modulation
Deep-Brain Stimulation — Entering the Era of Human Neural-Network Modulation
Journal Article

Deep-Brain Stimulation — Entering the Era of Human Neural-Network Modulation

2014
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Overview
The research of Alim Benabid and Mahlon DeLong — just recognized with the Lasker–Debakey Clinical Medical Research Award — has led to improved lives for more than 100,000 people with Parkinson's disease or other neurologic or neuropsychiatric disorders. Scribonius Largus, the court physician for the Roman emperor Claudius, used an electrical torpedo fish in 50 A.D. to treat headaches and gout. More than 1000 years elapsed before the idea of therapeutic brain stimulation was rekindled. In 1786, Luigi Galvani demonstrated that he could conduct electricity through the nerves in a frog's leg. Later, Alessandro Volta conducted electrical current through wires and built crude but effective battery sources. Yet none of these experimenters could have predicted the usefulness of their technology in treating human disease by applying an electrical current within the human brain. This year's Lasker–Debakey Clinical Medical . . .