Asset Details

MbrlCatalogueTitleDetail

Do you wish to reserve the book?

Genomic insights into the Ixodes scapularis tick vector of Lyme disease

by Massachusetts Institute of Technology (MIT) , Wortman, Jennifer R , Villar, Margarita , Universidade de Santiago de Compostela [España] = University of Santiago de Compostela [Spain] = Université de Saint-Jacques-de-Compostelle [Espagne] (USC) , Wikel, Stephen K , Université de Lausanne = University of Lausanne (UNIL) , Grimmelikhuijzen, Cornelis J. P , Park, Yoonseong , Universidade de Vigo , Department of Entomology ; Texas A&M University System , Wespiser, Adam R , Quinnipiac University , Virginia Polytechnic Institute and State University [Blacksburg] , University of Nevada ; Partenaires INRAE , Gillespie, Joseph J , Sanchez-Gracia, Alejandro , Zhu, Jiwei , Sakamoto, Joyce M , Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) , Ribeiro, Jose M , California State Polytechnic University [Pomona] (CAL POLY POMONA) , The University of Queensland (UQ [All campuses : Brisbane, Dutton Park Gatton, Herston, St Lucia and other locations]) , Lawson, Daniel , Department of Entomology ; Pennsylvania State University (Penn State) ;

in 631/208/212 / 692/699/1670/3/1615 / 82/81 / Detoxification / Disease transmission / Humanities and Social Sciences / Life history / Life Sciences / Lyme disease / multidisciplinary / Pathogens / Population structure / Science / Science (multidisciplinary) / Vector-borne diseases

2016

Yes Please

Hey, we have placed the reservation for you!

By the way, why not check out events that you can attend while you pick your title.

Oops! Something went wrong.

Looks like we were not able to place the reservation. Kindly try again later.

Are you sure you want to remove the book from the shelf?

Genomic insights into the Ixodes scapularis tick vector of Lyme disease

2016

Confirm

Do you wish to request the book?

Genomic insights into the Ixodes scapularis tick vector of Lyme disease

2016

Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy

How would you like to get it?

Submit

We have requested the book for you!

Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.

Oops! Something went wrong.

Looks like we were not able to place your request. Kindly try again later.

Journal Article

Genomic insights into the Ixodes scapularis tick vector of Lyme disease

Massachusetts Institute of Technology (MIT),

Wortman, Jennifer R,

Villar, Margarita,

Universidade de Santiago de Compostela [España] = University of Santiago de Compostela [Spain] = Université de Saint-Jacques-de-Compostelle [Espagne] (USC),

Wikel, Stephen K,

Université de Lausanne = University of Lausanne (UNIL),

Grimmelikhuijzen, Cornelis J. P,

Park, Yoonseong,

Universidade de Vigo,

Department of Entomology ; Texas A&M University System,

Wespiser, Adam R,

Quinnipiac University,

Virginia Polytechnic Institute and State University [Blacksburg],

University of Nevada ; Partenaires INRAE,

Gillespie, Joseph J,

Sanchez-Gracia, Alejandro,

Zhu, Jiwei,

Sakamoto, Joyce M,

Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC),

Ribeiro, Jose M,

California State Polytechnic University [Pomona] (CAL POLY POMONA),

The University of Queensland (UQ [All campuses : Brisbane, Dutton Park Gatton, Herston, St Lucia and other locations]),

Lawson, Daniel,

Department of Entomology ; Pennsylvania State University (Penn State) ;

2016

Overview

Ticks transmit more pathogens to humans and animals than any other arthropod. We describe the 2.1 Gbp nuclear genome of the tick, Ixodes scapularis (Say), which vectors pathogens that cause Lyme disease, human granulocytic anaplasmosis, babesiosis and other diseases. The large genome reflects accumulation of repetitive DNA, new lineages of retro-transposons, and gene architecture patterns resembling ancient metazoans rather than pancrustaceans. Annotation of scaffolds representing similar to 57% of the genome, reveals 20,486 protein-coding genes and expansions of gene families associated with tick-host interactions. We report insights from genome analyses into parasitic processes unique to ticks, including host 'questing', prolonged feeding, cuticle synthesis, blood meal concentration, novel methods of haemoglobin digestion, haem detoxification, vitellogenesis and prolonged off-host survival. We identify proteins associated with the agent of human granulocytic anaplasmosis, an emerging disease, and the encephalitis-causing Langat virus, and a population structure correlated to life-history traits and transmission of the Lyme disease agent.

Share this book

Add to My Shelf

Publisher

Nature Publishing Group,CCSD,Nature Publishing Group UK,Nature Portfolio

Subject

631/208/212

/ 692/699/1670/3/1615

/ 82/81

/ Detoxification

/ Disease transmission

/ Humanities and Social Sciences

/ Life history