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Tiotropium in Early-Stage Chronic Obstructive Pulmonary Disease

by Xie, Canmao , Hu, Bin , Zhu, Xiaodan , Zhao, Jianping , Chen, Tao , Ye, Changxiu , Hu, Guoping , Tian, Jia , Bai, Chunxue , Du, Xiufang , Zheng, Jinping , Xu, Yongjian , Zeng, Lingshan , Li, Yinhuan , Hu, Xiwei , Du, Juan , Wang, Changzheng , Ye, Xianwei , Li, Fenglei , Guan, Wei-jie , Li, Xiaochen , Yao, Weimin , Chen, Shuyun , Gui, Jianping , Tan, Hui , Chen, Yan , Wei, Liping , Chen, Gang , Ma, Xitao , Zhang, Xiangyan , Zeng, Lizhen , Li, Minjing , Huang, Ping , Liu, Shengming , Ma, Qianli , Yang, Changli , Zhao, Dongxing , Ran, Pixin , Liang, Biao , Lin, Yingxiang , Zhou, Yumin , Zhong, Nan-shan , Li, Ying , He, Bingwen , Li, Xiongbin , Luo, Xiangwen , Yu, Ronghuan , Ye, Weishu , Shi, Zhe , Zhi, Rongchang , Yu, Shuqing

in Administration, Inhalation / Aged / Bronchodilator Agents - adverse effects / Bronchodilator Agents - therapeutic use / Bronchodilators / Chronic obstructive pulmonary disease / Clinical trials / Disease Progression / Double-Blind Method / Drug therapy / Female / Forced Expiratory Volume - drug effects / Humans / Lung diseases / Male / Middle Aged / Obstructive lung disease / Pharmaceuticals / Pulmonary Disease, Chronic Obstructive - drug therapy / Pulmonary Disease, Chronic Obstructive - physiopathology / Quality of Life / Respiratory function / Tiotropium Bromide - adverse effects / Tiotropium Bromide - therapeutic use

2017

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2017

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2017

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Journal Article

Tiotropium in Early-Stage Chronic Obstructive Pulmonary Disease

Xie, Canmao,

Hu, Bin,

Zhu, Xiaodan,

Zhao, Jianping,

Chen, Tao,

Ye, Changxiu,

Hu, Guoping,

Tian, Jia,

Bai, Chunxue,

Du, Xiufang,

Zheng, Jinping,

Xu, Yongjian,

Zeng, Lingshan,

Li, Yinhuan,

Hu, Xiwei,

Du, Juan,

Wang, Changzheng,

Ye, Xianwei,

Li, Fenglei,

Guan, Wei-jie,

Li, Xiaochen,

Yao, Weimin,

Chen, Shuyun,

Gui, Jianping,

Tan, Hui,

Chen, Yan,

Wei, Liping,

Chen, Gang,

Ma, Xitao,

Zhang, Xiangyan,

Zeng, Lizhen,

Li, Minjing,

Huang, Ping,

Liu, Shengming,

Ma, Qianli,

Yang, Changli,

Zhao, Dongxing,

Ran, Pixin,

Liang, Biao,

Lin, Yingxiang,

Zhou, Yumin,

Zhong, Nan-shan,

Li, Ying,

He, Bingwen,

Li, Xiongbin,

Luo, Xiangwen,

Yu, Ronghuan,

Ye, Weishu,

Shi, Zhe,

Zhi, Rongchang,

Yu, Shuqing

2017

Overview

Patients with early-stage COPD were assigned to usual care plus tiotropium or placebo. Tiotropium resulted in better FEV 1 values. The annual decline in the prebronchodilator FEV 1 was similar in the two groups, but a benefit from tiotropium was seen in postbronchodilator FEV 1 .

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Publisher

Massachusetts Medical Society

Subject

Administration, Inhalation

/ Aged

/ Bronchodilator Agents - adverse effects

/ Bronchodilator Agents - therapeutic use

/ Bronchodilators

/ Chronic obstructive pulmonary disease

/ Clinical trials