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Transcatheter Aortic-Valve Implantation for Aortic Stenosis in Patients Who Cannot Undergo Surgery
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Transcatheter Aortic-Valve Implantation for Aortic Stenosis in Patients Who Cannot Undergo Surgery
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Journal Article
Transcatheter Aortic-Valve Implantation for Aortic Stenosis in Patients Who Cannot Undergo Surgery
2010
Overview
Patients with aortic stenosis underwent transfemoral transcatheter implantation of a balloon-expandable bovine pericardial aortic valve. One-year mortality was lower with the balloon-expandable valve than with standard therapy, but the risk of stroke was higher.
Aortic stenosis is an insidious disease with a long latency period
1
followed by rapid progression after the appearance of symptoms,
2
–
5
resulting in a high rate of death (approximately 50% in the first 2 years after symptoms appear) among untreated patients.
1
,
6
–
8
Surgical replacement of the aortic valve reduces symptoms and improves survival in patients with aortic stenosis,
9
–
11
and in the absence of serious coexisting conditions, the procedure is associated with low operative mortality.
12
,
13
However, in clinical practice, at least 30% of patients with severe symptomatic aortic stenosis do not undergo surgery for replacement of the aortic . . .
Publisher
Massachusetts Medical Society
Subject
/ Aortic Valve Stenosis - mortality
/ Aortic Valve Stenosis - surgery
/ Aortic Valve Stenosis - therapy
/ Biological and medical sciences
/ Cardiovascular Diseases - mortality
/ Endocardial and cardiac valvular diseases
/ Female
/ Heart
/ Heart Valve Prosthesis Implantation - methods
/ Humans
/ Male
/ Patients
/ Surgery
