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De novo genome assembly of Ansell's mole-rat (Fukomys anselli)
by
Begall, Sabine
, Wagner, Rebecca E
, Goncalves, Angela
, Busa, Veronica F
, Frye, Michaela
, Coimbra, Raphael
, Odom, Duncan T
, Behm, Mikaela
, Bekavac, Milica
in
Cancer research
/ Genetics
/ Genomes
/ Genomics
/ Humidity
/ Hypoxia
/ Medical research
/ Phylogenetics
/ Research centers
/ Rodents
/ Zoology
2026
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De novo genome assembly of Ansell's mole-rat (Fukomys anselli)
by
Begall, Sabine
, Wagner, Rebecca E
, Goncalves, Angela
, Busa, Veronica F
, Frye, Michaela
, Coimbra, Raphael
, Odom, Duncan T
, Behm, Mikaela
, Bekavac, Milica
in
Cancer research
/ Genetics
/ Genomes
/ Genomics
/ Humidity
/ Hypoxia
/ Medical research
/ Phylogenetics
/ Research centers
/ Rodents
/ Zoology
2026
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De novo genome assembly of Ansell's mole-rat (Fukomys anselli)
by
Begall, Sabine
, Wagner, Rebecca E
, Goncalves, Angela
, Busa, Veronica F
, Frye, Michaela
, Coimbra, Raphael
, Odom, Duncan T
, Behm, Mikaela
, Bekavac, Milica
in
Cancer research
/ Genetics
/ Genomes
/ Genomics
/ Humidity
/ Hypoxia
/ Medical research
/ Phylogenetics
/ Research centers
/ Rodents
/ Zoology
2026
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De novo genome assembly of Ansell's mole-rat (Fukomys anselli)
Journal Article
De novo genome assembly of Ansell's mole-rat (Fukomys anselli)
2026
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Overview
Ansell's mole-rat (Fukomys anselli) is an African rodent known for its subterranean lifestyle and unique phenotypic traits, including extreme longevity, magnetoreception, and a cooperative breeding social structure. Efforts to dissect the genetic architecture of these traits and to decipher their phylogenetic relationships within the broader African mole-rat family would greatly benefit from a reference-grade genome. Here, we report a first genome assembly of a male Ansell's mole-rat. By combining Oxford Nanopore Technologies long reads and Illumina short reads with Hi-C data, we generated a chromosome level assembly with a total length of 2.27 Gb, 412 scaffolds, and a scaffold N50 of 72.4 Mb. We identified 99.54% of expected genes and annotated 29,094 transcripts using RNA sequencing data. This high-quality de novo genome of F. anselli lays the foundation for dissecting the genetic and evolutionary basis of its extraordinary traits and resolving African mole-rat phylogeny.
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