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Changes in Diabetes-Related Complications in the United States, 1990–2010
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Changes in Diabetes-Related Complications in the United States, 1990–2010
Changes in Diabetes-Related Complications in the United States, 1990–2010
Journal Article

Changes in Diabetes-Related Complications in the United States, 1990–2010

2014
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Overview
Rates of diabetes-related complications have declined substantially in the past two decades. However, a large burden of disease persists because of the continued increase in the prevalence of diabetes. Twenty-one years ago, the Diabetes Control and Complications Trial (DCCT) showed that intensive glycemic control could reduce the microvascular complications of type 1 diabetes mellitus. 1 Subsequent studies showed that macrovascular and microvascular complications could be substantially reduced with tight control of glucose levels, blood pressure, and lipid levels in adults with type 2 diabetes. 2 – 5 Collectively, these studies focused attention on diabetes as a public health problem, with a course that could be altered by a combination of changes in clinical care (e.g., intensive management of risk factors), the health system (e.g., organization of care), health promotion (e.g., support for . . .