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Semaglutide in Patients with Heart Failure with Preserved Ejection Fraction and Obesity

by Møller, Daniél V. , Perna, Eduardo , Sharma, Kavita , Abildstrøm, Steen Z. , Abhayaratna, Walter , Rasmussen, Søren , Van der Meer, Peter , Petrie, Mark C , Kosiborod, Mikhail N. , Fu, Michael , Ahmed, Fozia Z. , Schou, Morten , Butler, Javed , Senni, Michele , Ezekowitz, Justin , Chopra, Vijay , Hovingh, G. Kees , Wolf, Dennis , Shah, Sanjiv J. , Davies, Melanie , Lindegaard, Marie L. , Ito, Hiroshi , von Lewinski, Dirk , Treppendahl, Marianne B. , Núñez, Julio , Borlaug, Barry A. , Merkely, Bela , Lelonek, Małgorzata , Melenovsky, Vojtech , Kitzman, Dalane W. , Verma, Subodh

in Antidiabetics / Body weight loss / C-reactive protein / Cardiology / Cardiomyopathy / Clinical Medicine / Clinical Medicine General / Congestive heart failure / Diabetes / Diet / Ejection fraction / Endocrinology / Gastroenterology / Gastrointestinal surgery / Glucagon-Like Peptides - adverse effects / Glucagon-Like Peptides - therapeutic use / Heart Failure / Heart Failure - complications / Heart Failure - drug therapy / Heart Failure - physiopathology / Humans / Intravenous therapy / Nutrition / Obesity / Obesity - complications / Overweight / Patients / Peptides / Placebos / Quality of life / Statistical analysis / Stroke Volume / Weight control

2023

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Semaglutide in Patients with Heart Failure with Preserved Ejection Fraction and Obesity

2023

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Semaglutide in Patients with Heart Failure with Preserved Ejection Fraction and Obesity

2023

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Journal Article

Semaglutide in Patients with Heart Failure with Preserved Ejection Fraction and Obesity

Møller, Daniél V.,

Perna, Eduardo,

Sharma, Kavita,

Abildstrøm, Steen Z.,

Abhayaratna, Walter,

Rasmussen, Søren,

Van der Meer, Peter,

Petrie, Mark C,

Kosiborod, Mikhail N.,

Fu, Michael,

Ahmed, Fozia Z.,

Schou, Morten,

Butler, Javed,

Senni, Michele,

Ezekowitz, Justin,

Chopra, Vijay,

Hovingh, G. Kees,

Wolf, Dennis,

Shah, Sanjiv J.,

Davies, Melanie,

Lindegaard, Marie L.,

Ito, Hiroshi,

von Lewinski, Dirk,

Treppendahl, Marianne B.,

Núñez, Julio,

Borlaug, Barry A.,

Merkely, Bela,

Lelonek, Małgorzata,

Melenovsky, Vojtech,

Kitzman, Dalane W.,

Verma, Subodh

2023

Overview

In patients with heart failure with preserved ejection fraction and obesity, semaglutide (2.4 mg) led to greater reductions in symptoms and physical limitations and greater improvements in exercise function than placebo.

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Publisher

Massachusetts Medical Society

Subject

/ Clinical Medicine General