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Partial Oral versus Intravenous Antibiotic Treatment of Endocarditis

by Schønheyder, Henrik C , Elming, Hanne , Jensen, Kaare T , Rosenvinge, Flemming , Iversen, Kasper , Tønder, Niels , Madsen, Trine , Bruun, Niels E , Torp-Pedersen, Christian , Moser, Claus , Ihlemann, Nikolaj , Fosbøll, Emil L , Høfsten, Dan E , Helweg-Larsen, Jannik , Gill, Sabine U , Christensen, Jens J , Schultz, Martin , Klein, Christine F , Køber, Lars , Fursted, Kurt , Bundgaard, Henning

in Administration, Intravenous / Administration, Oral / Aged / Anti-Bacterial Agents - administration & dosage / Anti-Bacterial Agents - adverse effects / Anti-Bacterial Agents - pharmacokinetics / Antibiotics / Bacteremia / Bacteremia - drug therapy / Cardiology / Coagulase / Endocarditis / Endocarditis, Bacterial - drug therapy / Endocarditis, Bacterial - microbiology / Endocarditis, Bacterial - mortality / Female / Heart / Heart surgery / Heart Valve Prosthesis - microbiology / Hospitals / Humans / Intention to Treat Analysis / Intravenous administration / Kaplan-Meier Estimate / Length of Stay / Male / Middle Aged / Patients / Recurrence / Society / Surgery

2019

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Partial Oral versus Intravenous Antibiotic Treatment of Endocarditis

2019

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2019

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Journal Article

Partial Oral versus Intravenous Antibiotic Treatment of Endocarditis

Schønheyder, Henrik C,

Elming, Hanne,

Jensen, Kaare T,

Rosenvinge, Flemming,

Iversen, Kasper,

Tønder, Niels,

Madsen, Trine,

Bruun, Niels E,

Torp-Pedersen, Christian,

Moser, Claus,

Ihlemann, Nikolaj,

Fosbøll, Emil L,

Høfsten, Dan E,

Helweg-Larsen, Jannik,

Gill, Sabine U,

Christensen, Jens J,

Schultz, Martin,

Klein, Christine F,

Køber, Lars,

Fursted, Kurt,

Bundgaard, Henning

2019

Overview

In this randomized, controlled trial conducted at Danish cardiac centers, intravenous antibiotic therapy was compared with partial oral antibiotic therapy for the treatment of bacterial endocarditis. The outcomes were similar in the two groups.

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Publisher

Massachusetts Medical Society

Subject

Administration, Intravenous

/ Administration, Oral

/ Aged

/ Anti-Bacterial Agents - administration & dosage

/ Anti-Bacterial Agents - adverse effects

/ Anti-Bacterial Agents - pharmacokinetics

/ Antibiotics