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Road traffic noise exposure and its impact on health: evidence from animal and human studies—chronic stress, inflammation, and oxidative stress as key components of the complex downstream pathway underlying noise-induced non-auditory health effects
by
Lertxundi, Aitana
, Lertxundi, Nerea
, Vegas, Oscar
, Bereziartua, Ainhoa
, Cruz, Maria Teresa
, Ferreira, Isabel
, Arregi, Ane
, Silva, Ana
in
Aging (artificial)
/ Animals
/ Aquatic Pollution
/ Cardiovascular diseases
/ Catecholamines
/ circadian rhythm
/ Circadian rhythms
/ Cognitive ability
/ cognitive disorders
/ cortisol
/ Earth and Environmental Science
/ Ecotoxicology
/ Environment
/ Environmental Chemistry
/ Environmental Exposure
/ Environmental Health
/ Health risks
/ Hormones
/ Humans
/ Hypothalamus
/ Inflammation
/ microbiome
/ Microbiomes
/ Neurodegenerative diseases
/ Noise - adverse effects
/ Noise levels
/ noise pollution
/ Noise, Transportation - adverse effects
/ Oxidative Stress
/ Pituitary
/ Public health
/ Review
/ Review Article
/ risk
/ Risk factors
/ Roads & highways
/ secretion
/ Stress response
/ Sympathetic nervous system
/ traffic
/ Transportation noise
/ urbanization
/ Waste Water Technology
/ Water Management
/ Water Pollution Control
2024
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Road traffic noise exposure and its impact on health: evidence from animal and human studies—chronic stress, inflammation, and oxidative stress as key components of the complex downstream pathway underlying noise-induced non-auditory health effects
by
Lertxundi, Aitana
, Lertxundi, Nerea
, Vegas, Oscar
, Bereziartua, Ainhoa
, Cruz, Maria Teresa
, Ferreira, Isabel
, Arregi, Ane
, Silva, Ana
in
Aging (artificial)
/ Animals
/ Aquatic Pollution
/ Cardiovascular diseases
/ Catecholamines
/ circadian rhythm
/ Circadian rhythms
/ Cognitive ability
/ cognitive disorders
/ cortisol
/ Earth and Environmental Science
/ Ecotoxicology
/ Environment
/ Environmental Chemistry
/ Environmental Exposure
/ Environmental Health
/ Health risks
/ Hormones
/ Humans
/ Hypothalamus
/ Inflammation
/ microbiome
/ Microbiomes
/ Neurodegenerative diseases
/ Noise - adverse effects
/ Noise levels
/ noise pollution
/ Noise, Transportation - adverse effects
/ Oxidative Stress
/ Pituitary
/ Public health
/ Review
/ Review Article
/ risk
/ Risk factors
/ Roads & highways
/ secretion
/ Stress response
/ Sympathetic nervous system
/ traffic
/ Transportation noise
/ urbanization
/ Waste Water Technology
/ Water Management
/ Water Pollution Control
2024
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Road traffic noise exposure and its impact on health: evidence from animal and human studies—chronic stress, inflammation, and oxidative stress as key components of the complex downstream pathway underlying noise-induced non-auditory health effects
by
Lertxundi, Aitana
, Lertxundi, Nerea
, Vegas, Oscar
, Bereziartua, Ainhoa
, Cruz, Maria Teresa
, Ferreira, Isabel
, Arregi, Ane
, Silva, Ana
in
Aging (artificial)
/ Animals
/ Aquatic Pollution
/ Cardiovascular diseases
/ Catecholamines
/ circadian rhythm
/ Circadian rhythms
/ Cognitive ability
/ cognitive disorders
/ cortisol
/ Earth and Environmental Science
/ Ecotoxicology
/ Environment
/ Environmental Chemistry
/ Environmental Exposure
/ Environmental Health
/ Health risks
/ Hormones
/ Humans
/ Hypothalamus
/ Inflammation
/ microbiome
/ Microbiomes
/ Neurodegenerative diseases
/ Noise - adverse effects
/ Noise levels
/ noise pollution
/ Noise, Transportation - adverse effects
/ Oxidative Stress
/ Pituitary
/ Public health
/ Review
/ Review Article
/ risk
/ Risk factors
/ Roads & highways
/ secretion
/ Stress response
/ Sympathetic nervous system
/ traffic
/ Transportation noise
/ urbanization
/ Waste Water Technology
/ Water Management
/ Water Pollution Control
2024
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Road traffic noise exposure and its impact on health: evidence from animal and human studies—chronic stress, inflammation, and oxidative stress as key components of the complex downstream pathway underlying noise-induced non-auditory health effects
Journal Article
Road traffic noise exposure and its impact on health: evidence from animal and human studies—chronic stress, inflammation, and oxidative stress as key components of the complex downstream pathway underlying noise-induced non-auditory health effects
2024
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Overview
In heavily urbanized world saturated with environmental pollutants, road traffic noise stands out as a significant factor contributing to widespread public health issues. It contributes in the development of a diverse range of non-communicable diseases, such as cardiovascular diseases, metabolic dysregulation, cognitive impairment, and neurodegenerative disorders. Although the exact mechanisms behind these non-auditory health effects remain unclear, the noise reaction model centres on the stress response to noise. When exposed to noise, the body activates the hypothalamic–pituitary–adrenal axis and the sympathetic nervous system, leading to the secretion of stress hormones like catecholamines and cortisol. Prolonged exposure to noise-induced stress results in chronic inflammation and oxidative stress. This review underscores the role of inflammation and oxidative stress in the progression of noise-induced vascular dysfunction, disruption of the circadian rhythm, accelerated aging, neuroinflammation, and changes in microbiome. Additionally, our focus is on understanding the interconnected nature of these health outcomes: These interconnected factors create a cascade effect, contributing to the accumulation of multiple risk factors that ultimately lead to severe adverse health effects.
Publisher
Springer Berlin Heidelberg,Springer Nature B.V
Subject
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