Asset Details
Do you wish to reserve the book?
Commercial software upgrades may significantly alter Perfusion CT parameter values in colorectal cancer
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Commercial software upgrades may significantly alter Perfusion CT parameter values in colorectal cancer
Do you wish to request the book?
Commercial software upgrades may significantly alter Perfusion CT parameter values in colorectal cancer
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Commercial software upgrades may significantly alter Perfusion CT parameter values in colorectal cancer
2011
Overview
Objective
To determine how commercial software platform upgrades impact on derived parameters for colorectal cancer.
Materials and methods
Following ethical approval, 30 patients with suspected colorectal cancer underwent Perfusion CT using integrated 64 detector PET/CT before surgery. Analysis was performed using software based on modified distributed parameter analysis (Perfusion software version 4; Perfusion 4.0), then repeated using the previous version (Perfusion software version 3; Perfusion 3.0). Tumour blood flow (BF), blood volume (BV), mean transit time (MTT) and permeability surface area product (PS) were determined for identical regions-of-interest. Slice-by-slice and ‘whole tumour’ variance was assessed by Bland-Altman analysis.
Results
Mean BF, BV and PS was 20.4%, 59.5%, and 106% higher, and MTT 14.3% shorter for Perfusion 4.0 than Perfusion 3.0. The mean difference (95% limits of agreement) were +13.5 (−44.9 to 72.0), +2.61 (−0.06 to 5.28), −1.23 (−6.83 to 4.36), and +14.2 (−4.43 to 32.8) for BF, BV, MTT and PS respectively. Within subject coefficient of variation was 36.6%, 38.0%, 27.4% and 60.6% for BF, BV, MTT and PS respectively indicating moderate to poor agreement.
Conclusion
Software version upgrades of the same software platform may result in significantly different parameter values, requiring adjustments for cross-version comparison.
Publisher
Springer-Verlag,Springer Nature B.V
Subject
Adenocarcinoma - diagnostic imaging
/ Aged
/ Blood
/ Colonic Neoplasms - diagnostic imaging
/ Colorectal Neoplasms - diagnostic imaging
/ Colorectal Neoplasms - surgery
/ Contrast Media - pharmacology
/ Female
/ Humans
/ Imaging
/ Iodine
/ Male
/ Medicine
/ Patients
/ Radiographic Image Interpretation, Computer-Assisted - instrumentation
/ Radiographic Image Interpretation, Computer-Assisted - methods
/ Rectal Neoplasms - diagnostic imaging
/ Software
