Asset Details
Do you wish to reserve the book?
Comparison of high-flux hemodialysis with hemodialysis filtration in treatment of uraemic pruritus: a randomized controlled trial
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Comparison of high-flux hemodialysis with hemodialysis filtration in treatment of uraemic pruritus: a randomized controlled trial
Do you wish to request the book?
Comparison of high-flux hemodialysis with hemodialysis filtration in treatment of uraemic pruritus: a randomized controlled trial
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Comparison of high-flux hemodialysis with hemodialysis filtration in treatment of uraemic pruritus: a randomized controlled trial
2016
Overview
Purpose
Uraemic pruritus (UP) is one of the most common complications in patients with end-stage renal disease (ESRD) undergoing dialysis and greatly undermines their quality of life. The present study was designed to compare the clinical effect of high-flux hemodialysis (HFHD) with hemodialysis filtration (HDF) in the treatment of UP in ESRD patients, and to explore the possible underlying mechanisms.
Materials and methods
In this 12-week randomized and controlled trial, the clinical efficacy of HFHD or HDF on UP patients undergoing dialysis was evaluated. A total of 51 uremia patients suffering from pruritus from January 2009 to May 2013 were recruited and randomly assigned to intervention (
n
= 27) and control (
n
= 24) groups. The control group was received only HDF therapy, and the intervention group underwent HFHD treatment three times a week for 12 weeks.
Results
The scores for Visual Analogue Scale in both two groups were obviously decreased, but the Visual Analogue Scale scores in the intervention group had a better improvement than the control group within 12 weeks. The PSQI and SF-12 values in the intervention group had a better improvement than the control group within 12 weeks. In comparison of the changes from baseline between the control groups, there was greater improvement in BUN, creatinine, calcium, phosphorus, PTH, β2-MG, histamine, CRP and IL-6 levels of intervention group.
Conclusions
Our results demonstrate that HFHD has a better efficacy in the treatment of UP than HDF. HFHD has an exactly therapeutical efficacy in the UP associated with the inhibition of microinflammation state in dialysis patients.
Publisher
Springer Netherlands,Springer Nature B.V
Subject
