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Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level
by
Que, Loretta
, Bacharier, Leonard B
, Castro, Mario
, LaForce, Craig
, Szefler, Stanley J
, Chmiel, James
, Jackson, Daniel
, Kraft, Monica
, Phipatanakul, Wanda
, Pongracic, Jacqueline A
, Holguin, Fernando
, Smith, Lewis
, Cabana, Michael D
, King, Tonya S
, Lazarus, Stephen C
, Mauger, David T
, Martinez, Fernando D
, DiMango, Emily
, Blake, Kathryn V
, Covar, Ronina
, Wenzel, Sally
, Chinchilli, Vernon M
, Gentile, Deborah
, Lemanske, Robert F
, Dyer, Anne-Marie
, Morgan, Wayne J
, Hastie, Annette
, Moore, Wendy
, Lugogo, Njira
, Israel, Elliot
, Krishnan, Jerry A
, Cardet, Juan C
, Denlinger, Loren
, Wechsler, Michael E
, Lang, Jason E
, Ross, Kristie
, Sorkness, Christine A
, Boushey, Homer A
, Fahy, John V
, Myers, Ross
, Woodruff, Prescott G
, Moy, James N
, Peters, Stephen P
, Fitzpatrick, Anne M
in
Acetylcholine receptors (muscarinic)
/ Administration, Inhalation
/ Adolescent
/ Adult
/ Asthma
/ Asthma - drug therapy
/ Asthma - immunology
/ Bronchodilator Agents - therapeutic use
/ Clinical trials
/ Cross-Over Studies
/ Double-Blind Method
/ Eosinophils
/ Female
/ Glucocorticoids
/ Glucocorticoids - therapeutic use
/ Humans
/ Inflammation
/ Leukocyte Count
/ Leukocytes (eosinophilic)
/ Male
/ Medication Adherence
/ Middle Aged
/ Mometasone Furoate - therapeutic use
/ Sputum
/ Sputum - immunology
/ Tiotropium Bromide - therapeutic use
/ Young Adult
2019
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Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level
by
Que, Loretta
, Bacharier, Leonard B
, Castro, Mario
, LaForce, Craig
, Szefler, Stanley J
, Chmiel, James
, Jackson, Daniel
, Kraft, Monica
, Phipatanakul, Wanda
, Pongracic, Jacqueline A
, Holguin, Fernando
, Smith, Lewis
, Cabana, Michael D
, King, Tonya S
, Lazarus, Stephen C
, Mauger, David T
, Martinez, Fernando D
, DiMango, Emily
, Blake, Kathryn V
, Covar, Ronina
, Wenzel, Sally
, Chinchilli, Vernon M
, Gentile, Deborah
, Lemanske, Robert F
, Dyer, Anne-Marie
, Morgan, Wayne J
, Hastie, Annette
, Moore, Wendy
, Lugogo, Njira
, Israel, Elliot
, Krishnan, Jerry A
, Cardet, Juan C
, Denlinger, Loren
, Wechsler, Michael E
, Lang, Jason E
, Ross, Kristie
, Sorkness, Christine A
, Boushey, Homer A
, Fahy, John V
, Myers, Ross
, Woodruff, Prescott G
, Moy, James N
, Peters, Stephen P
, Fitzpatrick, Anne M
in
Acetylcholine receptors (muscarinic)
/ Administration, Inhalation
/ Adolescent
/ Adult
/ Asthma
/ Asthma - drug therapy
/ Asthma - immunology
/ Bronchodilator Agents - therapeutic use
/ Clinical trials
/ Cross-Over Studies
/ Double-Blind Method
/ Eosinophils
/ Female
/ Glucocorticoids
/ Glucocorticoids - therapeutic use
/ Humans
/ Inflammation
/ Leukocyte Count
/ Leukocytes (eosinophilic)
/ Male
/ Medication Adherence
/ Middle Aged
/ Mometasone Furoate - therapeutic use
/ Sputum
/ Sputum - immunology
/ Tiotropium Bromide - therapeutic use
/ Young Adult
2019
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Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level
by
Que, Loretta
, Bacharier, Leonard B
, Castro, Mario
, LaForce, Craig
, Szefler, Stanley J
, Chmiel, James
, Jackson, Daniel
, Kraft, Monica
, Phipatanakul, Wanda
, Pongracic, Jacqueline A
, Holguin, Fernando
, Smith, Lewis
, Cabana, Michael D
, King, Tonya S
, Lazarus, Stephen C
, Mauger, David T
, Martinez, Fernando D
, DiMango, Emily
, Blake, Kathryn V
, Covar, Ronina
, Wenzel, Sally
, Chinchilli, Vernon M
, Gentile, Deborah
, Lemanske, Robert F
, Dyer, Anne-Marie
, Morgan, Wayne J
, Hastie, Annette
, Moore, Wendy
, Lugogo, Njira
, Israel, Elliot
, Krishnan, Jerry A
, Cardet, Juan C
, Denlinger, Loren
, Wechsler, Michael E
, Lang, Jason E
, Ross, Kristie
, Sorkness, Christine A
, Boushey, Homer A
, Fahy, John V
, Myers, Ross
, Woodruff, Prescott G
, Moy, James N
, Peters, Stephen P
, Fitzpatrick, Anne M
in
Acetylcholine receptors (muscarinic)
/ Administration, Inhalation
/ Adolescent
/ Adult
/ Asthma
/ Asthma - drug therapy
/ Asthma - immunology
/ Bronchodilator Agents - therapeutic use
/ Clinical trials
/ Cross-Over Studies
/ Double-Blind Method
/ Eosinophils
/ Female
/ Glucocorticoids
/ Glucocorticoids - therapeutic use
/ Humans
/ Inflammation
/ Leukocyte Count
/ Leukocytes (eosinophilic)
/ Male
/ Medication Adherence
/ Middle Aged
/ Mometasone Furoate - therapeutic use
/ Sputum
/ Sputum - immunology
/ Tiotropium Bromide - therapeutic use
/ Young Adult
2019
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Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level
Journal Article
Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level
2019
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Overview
In this trial involving patients with mild, persistent asthma, there was no significant difference in therapeutic effect between an inhaled glucocorticoid (mometasone) and placebo in patients with a low sputum eosinophil level (<2%), which was reported in nearly three quarters of the patients.
Publisher
Massachusetts Medical Society
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