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A systemic apolipoprotein A-IV-associated amyloidosis confirmed by proteome analysis
by
Takada Kohichi
, Takasawa Akira
, Moriki Asako
, Aoyama Tomoyuki
, Ono Yusuke
, Osanai Makoto
, Murata Masaki
, Murakami Taro
, Ikeda, Hiroshi
, Takasawa Kumi
, Magara Kazufumi
, Igaki Yusuke
, Murase Kazuyuki
, Kyuno Daisuke
in
Amyloidogenesis
/ Amyloidosis
/ Apolipoprotein A
/ Apolipoproteins
/ Case reports
/ Paraffin
/ Paraffins
/ Proteins
/ Proteomes
2021
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A systemic apolipoprotein A-IV-associated amyloidosis confirmed by proteome analysis
by
Takada Kohichi
, Takasawa Akira
, Moriki Asako
, Aoyama Tomoyuki
, Ono Yusuke
, Osanai Makoto
, Murata Masaki
, Murakami Taro
, Ikeda, Hiroshi
, Takasawa Kumi
, Magara Kazufumi
, Igaki Yusuke
, Murase Kazuyuki
, Kyuno Daisuke
in
Amyloidogenesis
/ Amyloidosis
/ Apolipoprotein A
/ Apolipoproteins
/ Case reports
/ Paraffin
/ Paraffins
/ Proteins
/ Proteomes
2021
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A systemic apolipoprotein A-IV-associated amyloidosis confirmed by proteome analysis
by
Takada Kohichi
, Takasawa Akira
, Moriki Asako
, Aoyama Tomoyuki
, Ono Yusuke
, Osanai Makoto
, Murata Masaki
, Murakami Taro
, Ikeda, Hiroshi
, Takasawa Kumi
, Magara Kazufumi
, Igaki Yusuke
, Murase Kazuyuki
, Kyuno Daisuke
in
Amyloidogenesis
/ Amyloidosis
/ Apolipoprotein A
/ Apolipoproteins
/ Case reports
/ Paraffin
/ Paraffins
/ Proteins
/ Proteomes
2021
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A systemic apolipoprotein A-IV-associated amyloidosis confirmed by proteome analysis
Journal Article
A systemic apolipoprotein A-IV-associated amyloidosis confirmed by proteome analysis
2021
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Overview
Amyloidosis is induced by extracellular deposition of certain proteins. Thirty-six proteins have so far been identified as amyloidogenic proteins in humans. Although it is very important to determine the specific amyloid protein type for the choice of therapy for amyloidosis patient, it might be difficult to identify specific proteins from amyloid-deposited tissue. Apolipoprotein A-IV is known as an amyloid-associated protein, but there have been few reports of apolipoprotein A-IV amyloidosis. Here we report a case of systemic apolipoprotein A-IV-associated amyloidosis that was confirmed by proteome analysis using formalin-fixed paraffin-embedded tissue and an immunohistochemical technique.
Publisher
Springer Nature B.V
Subject
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