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Atypical Femur Fracture Risk versus Fragility Fracture Prevention with Bisphosphonates

by Eastell, Richard , Black, Dennis M , Vittinghoff, Eric , Adams, Annette L , Ryan, Denison S , Dell, Richard M , Geiger, Erik J , Li, Bonnie H

in Age / Aged / Aged, 80 and over / Asian / Asian people / Bisphosphonates / Bone density / Bone Density Conservation Agents - adverse effects / Bone Density Conservation Agents - therapeutic use / Diphosphonates - adverse effects / Diphosphonates - therapeutic use / Electronic medical records / Female / Femoral Fractures - chemically induced / Femoral Fractures - epidemiology / Femoral Fractures - ethnology / Femur / Fractures / Glucocorticoids / Hip / Hip Fractures - epidemiology / Hip Fractures - prevention & control / Humans / Incidence / Middle Aged / Minority & ethnic groups / Multivariate Analysis / Osteoporosis / Osteoporosis, Postmenopausal - complications / Osteoporosis, Postmenopausal - drug therapy / Osteoporotic Fractures - chemically induced / Osteoporotic Fractures - epidemiology / Osteoporotic Fractures - prevention & control / Proportional Hazards Models / Risk Assessment / Risk Factors / Time Factors / White People / Womens health

2020

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Atypical Femur Fracture Risk versus Fragility Fracture Prevention with Bisphosphonates

by Eastell, Richard , Black, Dennis M , Vittinghoff, Eric , Adams, Annette L , Ryan, Denison S , Dell, Richard M , Geiger, Erik J , Li, Bonnie H

2020

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Atypical Femur Fracture Risk versus Fragility Fracture Prevention with Bisphosphonates

by Eastell, Richard , Black, Dennis M , Vittinghoff, Eric , Adams, Annette L , Ryan, Denison S , Dell, Richard M , Geiger, Erik J , Li, Bonnie H

2020

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Journal Article

Atypical Femur Fracture Risk versus Fragility Fracture Prevention with Bisphosphonates

Eastell, Richard,

Black, Dennis M,

Vittinghoff, Eric,

Adams, Annette L,

Ryan, Denison S,

Dell, Richard M,

Geiger, Erik J,

Li, Bonnie H

2020

Overview

In this study involving women 50 years of age or older who were receiving bisphosphonates, the risk of atypical femur fracture was very low as compared with the number of hip and other fractures that were prevented. Risk of atypical fractures increased with longer duration of bisphosphonate use and rapidly decreased after bisphosphonate discontinuation.

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Publisher

Massachusetts Medical Society

Subject

/ Aged

/ Asian