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Clinical Characteristics of Dementia Associated with Argyrophilic Grain Disease

by Steuerwald, Gertrud M. , Mittag, Michael , Tolnay, Markus , Taylor, Kirsten I. , Baumann, Thomas P. , Adams, Heiner , Monsch, Andreas U.

in Affect - physiology / Affective symptoms / Aged / Aged, 80 and over / Alzheimer's disease / Autopsy / Behavior - physiology / Behavior problems / Biological and medical sciences / Brain - pathology / Cognition / Cognition - physiology / Cognitive functioning / Cognitive-behavioral factors / Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases / Dementia / Dementia - etiology / Dementia - pathology / Dementia - psychology / Disease / Disease Progression / Errors of metabolism / Executive function / Female / Friendship / Grain / Humans / Lipids (lysosomal enzyme disorders, storage diseases) / Male / Medical sciences / Metabolic diseases / Neurodegenerative Diseases - pathology / Neurodegenerative Diseases - psychology / Neurology / Neuropsychological Tests / Original Research Article / Patients / Personality / Psychiatric Status Rating Scales / Psychomotor Performance - physiology / tau Proteins - physiology / Vascular diseases and vascular malformations of the nervous system

2007

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Clinical Characteristics of Dementia Associated with Argyrophilic Grain Disease

by Steuerwald, Gertrud M. , Mittag, Michael , Tolnay, Markus , Taylor, Kirsten I. , Baumann, Thomas P. , Adams, Heiner , Monsch, Andreas U.

2007

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Clinical Characteristics of Dementia Associated with Argyrophilic Grain Disease

by Steuerwald, Gertrud M. , Mittag, Michael , Tolnay, Markus , Taylor, Kirsten I. , Baumann, Thomas P. , Adams, Heiner , Monsch, Andreas U.

2007

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Journal Article

Clinical Characteristics of Dementia Associated with Argyrophilic Grain Disease

Steuerwald, Gertrud M.,

Mittag, Michael,

Tolnay, Markus,

Taylor, Kirsten I.,

Baumann, Thomas P.,

Adams, Heiner,

Monsch, Andreas U.

2007

Overview

Background/Aims: We aimed at characterizing the clinical features of dementia associated with argyrophilic grain disease (AgD). Methods: Relatives or close friends of 24 individuals with autopsy-confirmed AgD and 29 patients with autopsy-confirmed Alzheimer’s disease (AD) were administered a novel Retrospective Dementia Inventory to assess the cognitive, behavioral and affective symptoms of the deceased patients. Results: AgD patients showed less severe impairments in memory, language, attention and executive function than AD patients.Conclusion: Compared to AD patients, individuals suffering from AgD appear to present with comparable deficits in behavior and affect but relatively spared cognitive functioning.

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Publisher

Karger,S. Karger AG

Subject

Affect - physiology

/ Affective symptoms

/ Aged

/ Aged, 80 and over

/ Alzheimer's disease

/ Autopsy

/ Behavior - physiology