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A Trial of Intraoperative Low-Tidal-Volume Ventilation in Abdominal Surgery
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A Trial of Intraoperative Low-Tidal-Volume Ventilation in Abdominal Surgery
A Trial of Intraoperative Low-Tidal-Volume Ventilation in Abdominal Surgery
Journal Article

A Trial of Intraoperative Low-Tidal-Volume Ventilation in Abdominal Surgery

2013
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Overview
Low-tidal-volume ventilation with positive end-expiratory pressure is the standard of care in acute respiratory distress syndrome. In this trial, the use of protective ventilation during surgery, as compared with nonprotective ventilation, reduced postoperative complications. Worldwide, more than 230 million patients undergoing major surgery each year require general anesthesia and mechanical ventilation. 1 Postoperative pulmonary complications adversely affect clinical outcomes and health care utilization, 2 so prevention of these complications has become a measure of the quality of hospital care. 3 Previous, large cohort studies have shown that 20 to 30% of patients undergoing surgery with general anesthesia are at intermediate to high risk for postoperative pulmonary complications. 4 , 5 Mechanical ventilation with the use of high tidal volumes (10 to 15 ml per kilogram of predicted body weight) has traditionally been recommended to prevent hypoxemia and atelectasis in . . .