Asset Details
Do you wish to reserve the book?
CPAP for Prevention of Cardiovascular Events in Obstructive Sleep Apnea
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
CPAP for Prevention of Cardiovascular Events in Obstructive Sleep Apnea
Do you wish to request the book?
CPAP for Prevention of Cardiovascular Events in Obstructive Sleep Apnea
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
CPAP for Prevention of Cardiovascular Events in Obstructive Sleep Apnea
2016
Overview
In a randomized trial, over 2700 patients with obstructive sleep apnea and cardiovascular disease were assigned to CPAP plus usual care or to usual care alone. At a mean of 3.7 years, the rate of adverse cardiovascular events did not differ significantly between the groups.
Obstructive sleep apnea causes episodic hypoxemia and nocturnal sympathetic nervous system activation
1
and elevates blood pressure
2
and markers of oxidative stress, inflammation, and hypercoagulation.
3
,
4
Large negative intrathoracic pressure swings also impose mechanical stress on the heart and great vessels.
5
–
7
Population-based and sleep-clinic–based cohort studies have shown an association between obstructive sleep apnea and cardiovascular events,
8
–
16
particularly stroke.
17
Randomized, controlled trials have shown that treatment with continuous positive airway pressure (CPAP) lowers systolic blood pressure by 2 to 3 mm Hg in patients with normotensive obstructive sleep apnea
18
and by 6 to 7 mm Hg in patients with . . .
Publisher
Massachusetts Medical Society
Subject
/ Angina
/ Apnea
/ Cardiovascular Diseases - mortality
/ Cardiovascular Diseases - prevention & control
/ Cerebrovascular Disorders - complications
/ Continuous Positive Airway Pressure
/ Coronary Artery Disease - complications
/ Daytime
/ Female
/ Humans
/ Ischemia
/ Male
/ Mood
/ Sleep
/ Sleep Apnea, Obstructive - etiology
/ Sleep Apnea, Obstructive - therapy
/ Stroke
