Asset Details
Do you wish to reserve the book?
Time-trend costs of infection-related cancers in Japan: a systematic review
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Time-trend costs of infection-related cancers in Japan: a systematic review
Do you wish to request the book?
Time-trend costs of infection-related cancers in Japan: a systematic review
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Time-trend costs of infection-related cancers in Japan: a systematic review
2025
Overview
Introduction
Although infection-related cancers are largely preventable through vaccination and screening, the extent of their burden is not adequately addressed in developed countries, including Japan. This systematic review was conducted to analyze time trends in the economic burden of infection-related cancers in Japan.
Methods
We performed a systematic search on 14 cancers evidenced to be causally associated with five infectious agents, using PubMed and Scopus databases from their data inception to 2023. We selected English peer-reviewed articles that measured the monetary cost of infection-related cancers in Japan, regardless of cancer stage. Mixed methods of qualitative and quantitative analysis were conducted to thoroughly assess selected articles, following the PRISMA statement.
Results
Of the 820 documents initially included, 10 articles were retrieved for the final analysis. Most studies focused on the financial burden of stomach, liver, and cervical cancers. The total cost of three major infection-related cancers decreased significantly from 1746.2 billion yen (16,052.5 million USD) in 1996 to 885.9 billion yen (8297 million USD) in 2020. While the costs of stomach and liver cancers attributed to infections (Helicobacter pylori and Hepatitis B/Hepatitis C viruses) observed downward trends, the cost of cervical cancer related to Human papillomavirus (HPV) exhibited an upward trend.
Conclusion
Despite decreasing trends in the overall costs of infection-related cancers, the economic burden of HPV-related cervical cancer steadily increases in Japan. Alongside ongoing prevention for infection cancers in general, it is imperative to prioritize HPV vaccinations and related screening programs as a key focus in Japanese public health policy.
