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Cardiac-Resynchronization Therapy in Heart Failure with a Narrow QRS Complex
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Cardiac-Resynchronization Therapy in Heart Failure with a Narrow QRS Complex
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Journal Article
Cardiac-Resynchronization Therapy in Heart Failure with a Narrow QRS Complex
2013
Overview
In a randomized trial, patients with heart failure and a QRS duration of less than 130 msec were assigned to cardiac-resynchronization therapy (CRT) or no CRT. There were no significant differences in rates of death from any cause or hospitalization for heart failure.
Despite recent advances, heart failure remains a common cause of death and morbidity. According to current guidelines, cardiac-resynchronization therapy (CRT) is indicated for patients receiving stable medical therapy recommended by current guidelines who have moderate-to-severe heart failure, a left ventricular ejection fraction of 35% or less, and a QRS duration of 120 msec or more as assessed electrocardiographically.
1
However, many patients with heart failure have a QRS duration of less than 120 msec,
2
and it is currently not recommended that they receive CRT. Up to 50% of these patients show echocardiographic evidence of ventricular dyssynchrony
3
,
4
and hence might benefit . . .
Publisher
Massachusetts Medical Society
Subject
/ Biological and medical sciences
/ Cardiac Resynchronization Therapy - methods
/ Female
/ Heart
/ Heart failure, cardiogenic pulmonary edema, cardiac enlargement
/ Heart Failure, Systolic - diagnosis
/ Heart Failure, Systolic - mortality
/ Heart Failure, Systolic - therapy
/ Hospitalization - statistics & numerical data
/ Humans
/ Male
