Asset Details
Do you wish to reserve the book?
Measles immunity gaps and outbreak risk in a shifting landscape
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Measles immunity gaps and outbreak risk in a shifting landscape
Do you wish to request the book?
Measles immunity gaps and outbreak risk in a shifting landscape
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Measles immunity gaps and outbreak risk in a shifting landscape
2025
Overview
In The Lancet Infectious Diseases, Valentina Marziano and colleagues present an approach to quantify measles epidemiology, immunity, and outbreak risk. 2 Using rich case investigation data from Italy for the period 2013 to 2022 (which included demographic characteristics, vaccination status, case linkages, and an importation indicator), they defined infection episodes and analysed them by age, vaccination status, and setting. To estimate age-specific and region-specific residual susceptibility based on both vaccine-derived and infection-derived immunity, the authors fit a catalytic model to population-level aggregate measles case counts by age group and year. Marziano and colleagues addressed this limitation by incorporating their 2017 effective reproduction number (R e) estimates to calculate the probability of transmission given infectious contact using age-specific immunity profiles at the start of 2025 to then estimate the 2025 R e. The authors estimated R e to be greater than 1 at the national level (ranging from 1·31 to 1·78 across regions), indicating the potential for sustained measles virus transmission in Italy.
