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Unique Lipid A Modifications in Pseudomonas aeruginosa Isolated from the Airways of Patients with Cystic Fibrosis
by
Moskowitz, Samuel M.
, Miller, Samuel I.
, Kraig, Gretchen M.
, Harvey, Megan D.
, Adams, Kristin N.
, Ramsey, Bonnie
, Burns, Jane L.
, Ernst, Robert K.
, Emerson, Julia C.
, Speert, David P.
in
Antimicrobials
/ Arabinose - analogs & derivatives
/ Arabinose - analysis
/ Bacteria
/ Bacteriology
/ Biological and medical sciences
/ Bronchiectasis
/ Child
/ Child, Preschool
/ Chronic Disease
/ Cystic fibrosis
/ Cystic Fibrosis - epidemiology
/ Cystic Fibrosis - microbiology
/ Decanoic Acids - analysis
/ Fatty acids
/ Fundamental and applied biological sciences. Psychology
/ Humans
/ Infant
/ Infections
/ Lipid A - chemistry
/ Lipids
/ Lung diseases
/ Lung Diseases - epidemiology
/ Lung Diseases - microbiology
/ Microbiology
/ Miscellaneous
/ Palmitates
/ Palmitates - analysis
/ Prevalence
/ Pseudomonas aeruginosa
/ Pseudomonas aeruginosa - chemistry
/ Pseudomonas aeruginosa - classification
/ Pseudomonas aeruginosa - isolation & purification
/ Pseudomonas aeruginosa - pathogenicity
/ Pseudomonas Infections - epidemiology
/ Pseudomonas Infections - microbiology
/ Soil water
2007
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Unique Lipid A Modifications in Pseudomonas aeruginosa Isolated from the Airways of Patients with Cystic Fibrosis
by
Moskowitz, Samuel M.
, Miller, Samuel I.
, Kraig, Gretchen M.
, Harvey, Megan D.
, Adams, Kristin N.
, Ramsey, Bonnie
, Burns, Jane L.
, Ernst, Robert K.
, Emerson, Julia C.
, Speert, David P.
in
Antimicrobials
/ Arabinose - analogs & derivatives
/ Arabinose - analysis
/ Bacteria
/ Bacteriology
/ Biological and medical sciences
/ Bronchiectasis
/ Child
/ Child, Preschool
/ Chronic Disease
/ Cystic fibrosis
/ Cystic Fibrosis - epidemiology
/ Cystic Fibrosis - microbiology
/ Decanoic Acids - analysis
/ Fatty acids
/ Fundamental and applied biological sciences. Psychology
/ Humans
/ Infant
/ Infections
/ Lipid A - chemistry
/ Lipids
/ Lung diseases
/ Lung Diseases - epidemiology
/ Lung Diseases - microbiology
/ Microbiology
/ Miscellaneous
/ Palmitates
/ Palmitates - analysis
/ Prevalence
/ Pseudomonas aeruginosa
/ Pseudomonas aeruginosa - chemistry
/ Pseudomonas aeruginosa - classification
/ Pseudomonas aeruginosa - isolation & purification
/ Pseudomonas aeruginosa - pathogenicity
/ Pseudomonas Infections - epidemiology
/ Pseudomonas Infections - microbiology
/ Soil water
2007
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Unique Lipid A Modifications in Pseudomonas aeruginosa Isolated from the Airways of Patients with Cystic Fibrosis
by
Moskowitz, Samuel M.
, Miller, Samuel I.
, Kraig, Gretchen M.
, Harvey, Megan D.
, Adams, Kristin N.
, Ramsey, Bonnie
, Burns, Jane L.
, Ernst, Robert K.
, Emerson, Julia C.
, Speert, David P.
in
Antimicrobials
/ Arabinose - analogs & derivatives
/ Arabinose - analysis
/ Bacteria
/ Bacteriology
/ Biological and medical sciences
/ Bronchiectasis
/ Child
/ Child, Preschool
/ Chronic Disease
/ Cystic fibrosis
/ Cystic Fibrosis - epidemiology
/ Cystic Fibrosis - microbiology
/ Decanoic Acids - analysis
/ Fatty acids
/ Fundamental and applied biological sciences. Psychology
/ Humans
/ Infant
/ Infections
/ Lipid A - chemistry
/ Lipids
/ Lung diseases
/ Lung Diseases - epidemiology
/ Lung Diseases - microbiology
/ Microbiology
/ Miscellaneous
/ Palmitates
/ Palmitates - analysis
/ Prevalence
/ Pseudomonas aeruginosa
/ Pseudomonas aeruginosa - chemistry
/ Pseudomonas aeruginosa - classification
/ Pseudomonas aeruginosa - isolation & purification
/ Pseudomonas aeruginosa - pathogenicity
/ Pseudomonas Infections - epidemiology
/ Pseudomonas Infections - microbiology
/ Soil water
2007
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Unique Lipid A Modifications in Pseudomonas aeruginosa Isolated from the Airways of Patients with Cystic Fibrosis
Journal Article
Unique Lipid A Modifications in Pseudomonas aeruginosa Isolated from the Airways of Patients with Cystic Fibrosis
2007
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Overview
Three structural features of lipid A (addition of palmitate [C16 fatty acid], addition of aminoarabinose [positively charged amino sugar residue], and retention of 3-hydroxydecanoate [3-OH C10 fatty acid]) were determined for Pseudomonas aeruginosa isolates from patientswith cystic fibrosis (CF; n = 86), from the environment (n = 13), and from patients with other conditions (n = 14). Among P. aeruginosa CF isolates, 100% had lipid A with palmitate, 24.6% with aminoarabinose, and 33.3% retained 3-hydroxydecanoate. None of the isolates from the environment or from patients with other conditions displayed these modifications. These results indicate that unique lipid A modifications occur in clinical P. aeruginosa CF isolates.
Publisher
The University of Chicago Press,University of Chicago Press
Subject
/ Arabinose - analogs & derivatives
/ Bacteria
/ Biological and medical sciences
/ Child
/ Cystic Fibrosis - epidemiology
/ Cystic Fibrosis - microbiology
/ Fundamental and applied biological sciences. Psychology
/ Humans
/ Infant
/ Lipids
/ Lung Diseases - epidemiology
/ Lung Diseases - microbiology
/ Pseudomonas aeruginosa - chemistry
/ Pseudomonas aeruginosa - classification
/ Pseudomonas aeruginosa - isolation & purification
/ Pseudomonas aeruginosa - pathogenicity
/ Pseudomonas Infections - epidemiology
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