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Comment on “Transversus abdominis plane block with liposomal bupivacaine versus continuous epidural analgesia for major abdominal surgery: The EXPLANE randomized trial”
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Journal Article
Comment on “Transversus abdominis plane block with liposomal bupivacaine versus continuous epidural analgesia for major abdominal surgery: The EXPLANE randomized trial”
2022
Overview
[...]in the results section, the authors found that median opioid consumption during the initial 3 postoperative days in patients with TAP blocks was 56 mg intravenous morphine milligram equivalents (MMEs), which was 60% higher than the median opioid consumption in patients with epidural analgesia (35 mg). [...]in Supplemental Table 5 of Turan et al’ article reporting opioid consumption in 12-h intervals after surgery, we found that MMEs of median opioid consumptions in first, second and third 24 h postoperatively were 43.6, 36.2 and 29.1 mg in patients with TAP blocks, and 24.6, 24.7 and 20.1 mg in patients with epidural analgesia. [...]the results of a recent meta-analysis by Desai et al. comparing the postoperative analgesic efficacy and side-effect profile of TAP blocks with epidural analgesia in patients undergoing abdominal surgery also support the opioid-sparing effect of epidural analgesia [4].
Publisher
Elsevier Inc,Elsevier Limited
Subject
