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Antibody levels to hantavirus in inhabitants of western Santa Catarina State, Brazil
by
Figueiredo, Luiz Tadeu Moraes
, Padua, Michelly de
, Miranda, Gustavo Borba de
, Souza, William Marciel de
, Boff, Everton
, Disner, Geonildo Rodrigo
, Machado, Aline Rafaela da Silva Rodrigues
, Machado, Alex Martins
in
Adult
/ Aged
/ Antibodies, Viral - blood
/ Argentina
/ Biological and medical sciences
/ Brazil
/ Brazil - epidemiology
/ Enzyme-Linked Immunosorbent Assay
/ Epidemiology
/ Female
/ Fluorescent Antibody Technique
/ General aspects
/ Hantavirus
/ Hantavirus - immunology
/ Hantavirus Infections - diagnosis
/ Hantavirus Infections - epidemiology
/ Humans
/ Immunoglobulin G - blood
/ Male
/ Medical sciences
/ Middle Aged
/ Santa Catarina
/ TROPICAL MEDICINE
/ Young Adult
2012
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Antibody levels to hantavirus in inhabitants of western Santa Catarina State, Brazil
by
Figueiredo, Luiz Tadeu Moraes
, Padua, Michelly de
, Miranda, Gustavo Borba de
, Souza, William Marciel de
, Boff, Everton
, Disner, Geonildo Rodrigo
, Machado, Aline Rafaela da Silva Rodrigues
, Machado, Alex Martins
in
Adult
/ Aged
/ Antibodies, Viral - blood
/ Argentina
/ Biological and medical sciences
/ Brazil
/ Brazil - epidemiology
/ Enzyme-Linked Immunosorbent Assay
/ Epidemiology
/ Female
/ Fluorescent Antibody Technique
/ General aspects
/ Hantavirus
/ Hantavirus - immunology
/ Hantavirus Infections - diagnosis
/ Hantavirus Infections - epidemiology
/ Humans
/ Immunoglobulin G - blood
/ Male
/ Medical sciences
/ Middle Aged
/ Santa Catarina
/ TROPICAL MEDICINE
/ Young Adult
2012
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Antibody levels to hantavirus in inhabitants of western Santa Catarina State, Brazil
by
Figueiredo, Luiz Tadeu Moraes
, Padua, Michelly de
, Miranda, Gustavo Borba de
, Souza, William Marciel de
, Boff, Everton
, Disner, Geonildo Rodrigo
, Machado, Aline Rafaela da Silva Rodrigues
, Machado, Alex Martins
in
Adult
/ Aged
/ Antibodies, Viral - blood
/ Argentina
/ Biological and medical sciences
/ Brazil
/ Brazil - epidemiology
/ Enzyme-Linked Immunosorbent Assay
/ Epidemiology
/ Female
/ Fluorescent Antibody Technique
/ General aspects
/ Hantavirus
/ Hantavirus - immunology
/ Hantavirus Infections - diagnosis
/ Hantavirus Infections - epidemiology
/ Humans
/ Immunoglobulin G - blood
/ Male
/ Medical sciences
/ Middle Aged
/ Santa Catarina
/ TROPICAL MEDICINE
/ Young Adult
2012
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Antibody levels to hantavirus in inhabitants of western Santa Catarina State, Brazil
Journal Article
Antibody levels to hantavirus in inhabitants of western Santa Catarina State, Brazil
2012
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Overview
Hantavirus cardiopulmonary syndrome (HCPS) is an infectious disease caused by hantaviruses of the family Bunyaviridae, and is transmitted by aerosols of excreta of infected rodents. The aim of the present study was to determine antibody levels to hantavirus in the population that lives at frontier of Brazil and Argentina. Participated of the study 405 individuals living in the municipalities of Bandeirante, Santa Helena, Princesa and Tunapolis, state of Santa Catarina, Brazil. IgG antibodies to hantavirus were analyzed in sera by an ELISA that uses a recombinant N protein of Araraquara hantavirus as antigen. The results were also confirmed by immunofluorescent test. Eight individuals showed antibodies to hantavirus (1.97% positivity), with serum titers ranging from 100 to 800. Six seropositives were males, older than 30 years and farmers. Our results reinforce previous data on hantavirus circulation and human infections in the southern border of Brazil with Argentina. Síndrome Cardiopulmonar por Hantavírus (HCPS) é uma doença emergente, causada pelo gênero hantavírus membro da família Bunyaviridae, e são transmitidos aos humanos por aerossol de roedores infectados. O objetivo principal deste estudo foi determinar os níveis de anticorpos para hantavírus em uma população de residentes na fronteira do Brasil com a Argentina. Participaram deste estudo 405 indivíduos que moravam nos municípios de Bandeirante, Santa Helena, Princesa e Tunapólis, no estado de Santa Catarina, Brasil. Os anticorpos IgG para hantavírus foram analisados no soro por um ELISA que usa a nucleoproteína recombinante do vírus Araraquara como antígeno, posteriormente confirmados por imunofluorescência. Oito indivíduos apresentavam anticorpos para hantavírus (1.97% positivo), com titulo entre 100 a 800. Seis soropositivos foram homens, com idade superior a 30 anos e agricultores. Nossos resultados reforçam a circulação do hantavírus e infecção humana na fronteira do Brasil com a Argentina
Publisher
Instituto de Medicina Tropical de São Paulo,Instituto de Medicina Tropical de Sao Paulo,Instituto de Medicina Tropical,Universidade de São Paulo (USP)
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