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Microhemorrhages in MELAS Lesions: A Case Report
by
Martens, Evelien
, Verhaaren, Benjamin
, Demeestere, Jelle
in
Aphasia
/ Lesions
/ Magnetic resonance imaging
/ melas
/ microbleeds
/ microhemorrhages
/ mri
/ Mutation
/ Pathogenesis
/ Stroke
/ stroke-like episodes
2022
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Microhemorrhages in MELAS Lesions: A Case Report
by
Martens, Evelien
, Verhaaren, Benjamin
, Demeestere, Jelle
in
Aphasia
/ Lesions
/ Magnetic resonance imaging
/ melas
/ microbleeds
/ microhemorrhages
/ mri
/ Mutation
/ Pathogenesis
/ Stroke
/ stroke-like episodes
2022
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Journal Article
Microhemorrhages in MELAS Lesions: A Case Report
2022
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Overview
Introduction: Microhemorrhages have not been described in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes syndrome (MELAS) on magnetic resonce imaging (MRI). Main symptoms and/or important findings: A MELAS-patient had a rapid succession of 3 stroke-like episodes with dysphasia, visual field deficits and paresis of the right arm. MRI showed a lesion with corticosubcortical vasogenic edema without reduced diffusion, conforming to a stroke-like MELAS-lesion. Microhemorrhages within MELAS-lesions were detected on MRI. The main diagnoses, therapeutic interventions, and outcomes: Microhemorrhages are an atypical imaging finding in MELAS. The patient was treated with L-arginine.Conclusion: Microhemorrhages can present on MRI in (sub)acute MELAS lesions and may reflect mitochondrial microangiopathy.
Publisher
Ubiquity Press
Subject
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