Asset Details
Do you wish to reserve the book?
Colorectal Cancer: From Pathophysiology to Novel Therapeutic Approaches
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Colorectal Cancer: From Pathophysiology to Novel Therapeutic Approaches
Do you wish to request the book?
Colorectal Cancer: From Pathophysiology to Novel Therapeutic Approaches
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Colorectal Cancer: From Pathophysiology to Novel Therapeutic Approaches
2021
Overview
According to the Global Cancer Statistics 2020, colorectal cancer (CRC) represents the third most frequent malignancy worldwide, and is the second in terms of mortality [1]. Since the early 2000s, screening programs and the consequent early identification and removal of pre-cancerous lesions, together with the shift to a healthier lifestyle, have reduced the frequency of CRC cases in high-incidence areas [2,3]. Another mechanism of drug resistance may also be related to the therapy-induced selection of cancer stem cells, which represent tumor cells that are able to self-renew and to generate tumor cells harboring different genetic alterations [20]. [...]understanding their molecular features may be useful for developing therapeutic strategies that are able to target cancer stem cells and to overcome drug resistance. [...]although the knowledge of the mechanisms underlying the pathogenesis, progression, and metastasization of CRC has greatly expanded in recent decades, many aspects still remain to be clarified.
Publisher
MDPI AG,MDPI
Subject
