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Discovering the Hippo pathway protein-protein interactome
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Journal Article
Discovering the Hippo pathway protein-protein interactome
2014
Overview
The Hippo pathway is a signal transduction pathway that regulates organ growth, stem cell biology, regeneration and cancer. Three recent proteomic studies with Hippo path- way components uncovered extensive networks of interacting proteins revealing novel connections to cellcell junctions, regulation by vesicle trafficking, and phosphorylation- dependent remodeling of the interactome, and provide a rich landscape of novel interactors ripe for mechanistic studies.
Publisher
Nature Publishing Group UK,Nature Publishing Group
