Journal Article

Improving Daytime Functioning, Work Performance, and Quality of Life in Postmenopausal Women With Insomnia: Comparing Cognitive Behavioral Therapy for Insomnia, Sleep Restriction Therapy, and Sleep Hygiene Education

Roehrs, Timothy, Arnedt, J. Todd, Atkinson, Rachel L., Drake, Christopher L., Kalmbach, David A., Cheng, Philip, Cuamatzi-Castelan, Andrea, Fellman-Couture, Cynthia

2019

Overview

Study Objectives: Insomnia is a chief complaint among postmenopausal women, and insomnia impairs daytime functioning and reduces quality of life. Recent evidence supports the efficacy of cognitive behavioral therapy for insomnia (CBTI) for menopausal insomnia, but it remains unclear whether treating insomnia improves daytime function in this population. This study evaluated whether CBTI improves daytime fatigue, energy, self-reported sleepiness, work productivity, and quality of life in postmenopausal women with insomnia, and whether sleep restriction therapy (SRT)—a single component of CBTI—is equally efficacious. Methods: Single-site, randomized control trial. One hundred fifty postmenopausal women (56.44 ± 5.64 years) with perimenopausal or postmenopausal onset or exacerbation of chronic insomnia were randomized to 3 treatment conditions: sleep hygiene education control (SHE), SRT, and CBTI. Blinded assessments were performed at pretreatment, posttreatment, and 6-month follow-up. Results: CBTI and SRT produced moderate-to-large improvements in fatigue, energy, sleepiness, and work function at posttreatment and 6 months later. The CBTI group reported better quality of life as indicated by substantial improvements in emotional wellbeing and resiliency to physical and emotional problems, whereas the SRT and SHE groups only showed improvements in resiliency to physical problems. Pain complaints decreased as sleep improved but were not associated with specific treatment conditions. Similarly, insomnia remitters reported fewer daytime and nighttime hot flashes, although reductions were not associated with any specific treatment. Conclusions: CBTI and SRT are efficacious options for postmenopausal women with chronic insomnia. Both interventions improve daytime function, quality of life, and work performance, although CBTI produces superior results including the added benefit of improved emotional health. Clinical Trial Registration: Registry: ClinicalTrials.gov; Title: Behavioral Treatment of Menopausal Insomnia; Sleep and Daytime Outcomes; Identifier: NCT01933295; URL: https://clinicaltrials.gov/ct2/show/record/NCT01933295 Citation: Kalmbach DA, Cheng P, Arnedt JT, Cuamatzi-Castelan A, Atkinson RL, Fellman-Couture C, Roehrs T, Drake CL. Improving daytime functioning, work performance, and quality of life in postmenopausal women with insomnia: comparing cognitive behavioral therapy for insomnia, sleep restriction therapy, and sleep hygiene education. J Clin Sleep Med 2019;15(7):999–1010.

• Publisher: Springer International Publishing,Springer Nature B.V,American Academy of Sleep Medicine
• Subject: Behavior modification / Behavior Therapy - methods / Cognitive behavioral therapy / Cognitive Behavioral Therapy - methods / Comorbidity / Fatigue / Female / Hormone replacement therapy / Hot flash / Humans / Hygiene / Insomnia / Intervention / Job performance / Menopause / Middle age / Middle Aged / Patient Education as Topic - methods / Patients / Postmenopause / Quality of Life / Scientific Investigations / Sleep apnea / Sleep Hygiene / Sleep Initiation and Maintenance Disorders - therapy / Surveys and Questionnaires / Treatment Outcome / Womens health / Work Performance - statistics & numerical data