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Ivabradine–Flecainide as Breakthrough Drug Combination for Congenital Junctional Ectopic Tachycardia: A Case Report and Literature Review
by
Tipo, Vincenzo
, Pagano, Annamaria
, Di Marco, Giovanni Maria
, Pepe, Angela
, Di Nardo, Giangiacomo
, De Nigris, Angelica
in
Antiarrhythmic agents
/ Antiarrhythmics
/ Cardiac arrhythmia
/ Case Report
/ Case reports
/ congenital
/ Drug dosages
/ Heart rate
/ Heart surgery
/ Hypothyroidism
/ Informed consent
/ ivabradine
/ junctional
/ Literature reviews
/ Pacemakers
/ Patients
/ Pediatrics
/ Sinuses
/ Tachyarrhythmia
/ Tachycardia
2021
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Ivabradine–Flecainide as Breakthrough Drug Combination for Congenital Junctional Ectopic Tachycardia: A Case Report and Literature Review
by
Tipo, Vincenzo
, Pagano, Annamaria
, Di Marco, Giovanni Maria
, Pepe, Angela
, Di Nardo, Giangiacomo
, De Nigris, Angelica
in
Antiarrhythmic agents
/ Antiarrhythmics
/ Cardiac arrhythmia
/ Case Report
/ Case reports
/ congenital
/ Drug dosages
/ Heart rate
/ Heart surgery
/ Hypothyroidism
/ Informed consent
/ ivabradine
/ junctional
/ Literature reviews
/ Pacemakers
/ Patients
/ Pediatrics
/ Sinuses
/ Tachyarrhythmia
/ Tachycardia
2021
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Ivabradine–Flecainide as Breakthrough Drug Combination for Congenital Junctional Ectopic Tachycardia: A Case Report and Literature Review
by
Tipo, Vincenzo
, Pagano, Annamaria
, Di Marco, Giovanni Maria
, Pepe, Angela
, Di Nardo, Giangiacomo
, De Nigris, Angelica
in
Antiarrhythmic agents
/ Antiarrhythmics
/ Cardiac arrhythmia
/ Case Report
/ Case reports
/ congenital
/ Drug dosages
/ Heart rate
/ Heart surgery
/ Hypothyroidism
/ Informed consent
/ ivabradine
/ junctional
/ Literature reviews
/ Pacemakers
/ Patients
/ Pediatrics
/ Sinuses
/ Tachyarrhythmia
/ Tachycardia
2021
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Ivabradine–Flecainide as Breakthrough Drug Combination for Congenital Junctional Ectopic Tachycardia: A Case Report and Literature Review
Journal Article
Ivabradine–Flecainide as Breakthrough Drug Combination for Congenital Junctional Ectopic Tachycardia: A Case Report and Literature Review
2021
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Overview
Congenital junctional ectopic tachycardia (CJET) is a rare tachyarrhythmia that remains difficult to manage, with suboptimal control in most cases. Here, we report literature research on the use of ivabradine in the treatment of pediatric junctional ectopic tachycardia (JET), both congenital and postoperative, and describe the successful use of ivabradine–flecainide association for CJET therapy resistant to other antiarrhythmic agents. This new drug combination was effective in completely suppressing JET. Ivabradine–flecainide combination may be considered a new therapeutic strategy of CJET with a satisfactory efficacy/tolerability ratio in patients resistant to conventional drug combinations.
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