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Detection of human herpes virus 6 DNA in fetal hydrops

by Klapper, Paul E , Moore, Lynette , Al-Jiffri, Osama , Ashshi, Ahmed M , Cooper, Robert J

in Biological and medical sciences / Chromosome aberrations / Deoxyribonucleic acid / Diseases of mother, fetus and pregnancy / DNA / DNA, Viral - isolation & purification / Female / Fetuses / Genes / Genome, Viral / Gestational Age / Gynecology. Andrology. Obstetrics / Herpesvirus 6, Human - genetics / Herpesvirus 6, Human - isolation & purification / Humans / Hydrops Fetalis - pathology / Hydrops Fetalis - virology / Infant, Newborn / Male / Medical sciences / Polymerase Chain Reaction / Pregnancy. Fetus. Placenta / Restriction Mapping / Viruses

2000

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Detection of human herpes virus 6 DNA in fetal hydrops

by Klapper, Paul E , Moore, Lynette , Al-Jiffri, Osama , Ashshi, Ahmed M , Cooper, Robert J

2000

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Detection of human herpes virus 6 DNA in fetal hydrops

by Klapper, Paul E , Moore, Lynette , Al-Jiffri, Osama , Ashshi, Ahmed M , Cooper, Robert J

2000

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Journal Article

Detection of human herpes virus 6 DNA in fetal hydrops

Klapper, Paul E,

Moore, Lynette,

Al-Jiffri, Osama,

Ashshi, Ahmed M,

Cooper, Robert J

2000

Overview

Human herpes virus 6 (HHV6) DNA was detected in two of eight fetuses with hydrops and none of ten non-hydropic dead fetuses. Both cases with HHV6 DNA had chromosomal abnormalities. Positive results were confirmed with a second PCR specific for an alternate region of the HHV6 genome. Restriction endonuclease analysis confirmed that the viral DNA was representative of HHV6 type A.

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Publisher

Elsevier Ltd,Lancet,Elsevier Limited

Subject

Biological and medical sciences

/ Chromosome aberrations

/ Deoxyribonucleic acid

/ Diseases of mother, fetus and pregnancy

/ DNA

/ DNA, Viral - isolation & purification

/ Female