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Recent Advances in Synthesis and Applications of Calixarene Derivatives Endowed with Anticancer Activity
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Recent Advances in Synthesis and Applications of Calixarene Derivatives Endowed with Anticancer Activity
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Journal Article
Recent Advances in Synthesis and Applications of Calixarene Derivatives Endowed with Anticancer Activity
2024
Overview
Calix[n]arenes, macrocycles constituted of 4–8 phenol moieties linked through methylene bridges, are stable molecules that can be selectively functionalised at the upper or lower rim. It has already been demonstrated that calixarene derivatives can be biologically or pharmacologically active compounds. More recently, suitably functionalised calixarenes and calixarene analogues (dihomooxacalixarenes, thiacalixarenes, calix[4]resorcinols, azacalixarenes, calixpyrroles, and pillarenes) were found to act as anticancer agents, at least in in vitro assays. We are reporting on the latest progress in this research field.
Publisher
MDPI AG,MDPI
